Chemistry 237 Structure and Synthesis Spring 2015 Lecture 1 – January 20, 2014Why Experimental Organic Chemistry? http://www.energyinst.org.uk/ http://www.roadtrucker.com/ http://images.teamsugar.com/ http://www.wikipedia.org/Why Organic Chemistry? All pharmaceuticals Plastics, fabrics, adhesives, dyes, refrigerants Electronics, communications Energy (gasoline, catalysts, solar cells) Soaps, detergents Nexium vs. Prilosec (Esomeprazole) aspirin ibuprofen penicillin prozac valiumChem 237 People Teaching Assistants Section email Chris Pattillo AB1/AB4 [email protected] Daniel Holycross AB1/AB4 [email protected] Robert Zhang AB2/AB5 [email protected] Lab Manager: Randy Wilkey 250 NL [email protected] If you drop the lab or changes sections, notify Randy and the Chemistry Learning Center ([email protected]) Instructor: Professor Steven C. ZimmermanChem237 Course Objectives Overall Objective: to learn and apply the basic techniques and concepts of experimental organic chemistry Learn methods for isolation, purification and characterization of compounds Learn methods for maintaining accurate records and for reporting experimental results Develop critical thinking and problem-solving skills with respect to organic chemistryChem237 Course Content Reactions Acid-catalyzed rearrangement Esterification Diels-Alder Cycloaddition Hydride Reduction Etherification Claisen-Schmidt (aldol condensation)Chem237 Course Content Methods for Purification/Indentification recrystallization liquid-liquid extraction distillation (simple and fractional) thin-layer and column chromatography gas chromatography Spectroscopic Methods for Identification infrared spectroscopy NMR spectroscopyChem237 Required Materials Syllabus: Chemistry 237 Email copy and available on course website – see IllinoisCompass2g Text: “Operational Organic Chemistry” John W. Lehman, 4th Edition, Pearson Prentice Hall, 2009 Usage Card: Purchase at Illini Union Bookstore Laboratory Goggles: Must be approved goggles. Eye glasses are not acceptable. Labcoat Organic Chemistry Laboratory Notebook: Chemical Education Resources, Inc.Recommended Materials Model Set good for all your organic coursesChem237 Tools for Success Textbook Read assigned reading every week Helpful hints and problem solving tips Useful to answer post-lab questions Lectures Theory behind experiments and techniques Emphasis of important points in experiment Helpful hints and tips Attendance is required!Syllabus Experiment and Reading Schedule Safety Information How to perform basic techniques How to write your Pre-lab and Lab Reports Experimental procedures Post-lab questions – will be posted later Web Illinois Compass Website Your user name and password are initially set to your Net ID CHEMNET tutorials (recommended) Discussion Board on course website Office hours (Friday 4-5 pm) Chem237 Tools for SuccessChem237 How to Succeed BE PREPARED!! Read the experiments in advance and come to lab ready to start; do the Pre-lab writeup Familiarize yourself with the background information provided in recommended reading. WORK EFFICIENTLY!! Plan the optimal use of the laboratory period. Multitasking is important! Prepare for later steps during long reaction periods, distillations, etc. Don’t be afraid to ask questions!!!Exams Exam dates Exam 1: Week of March 17 Exam 2: Week of April 28 Quiz 1: Never - No Quizzes! Quiz 2: Never - No Quizzes Will cover material covered in lecture, assigned reading, and experiments Questions will be drawn from theory as well as practical material You are responsible for all assigned material for the exams.Grading Scheme Lab Reports............................................375 TA Grade ...............................................…50 Quiz 1 ........................................................00 Quiz 2 .......................................................00 Exam 1 .....................................................100 Exam 2 ..................................................…100 Total Points for the Course ...............625Distribution of Points per Experiment Expt 1 Isolation of BC Powder 40 Expt 2 Banana Oil 40 Expt 3 Conj. Diene in Eucalyptus Oil 85 Expt 4 NMR (dry lab) -- -- Acetylation of Ferrocene -- Expt 5 Unexpected Diol Reaction 85 Expt 6 Multi-step Synthesis 85 Expt 7 Synthesis of Chalcone 40 Total 400Cheating No forms of cheating will be tolerated Copying of lab reports, pre-labs, or notebooks will result in a failing grade for the course Faking data will result in a failing grade for the course Student ID’s will be checked at exams For more info see the Student Code, Article 1: Student Rights and Responsibilities, Part 4: Academic Integrity at http://www.fs.uiuc.edu:1503/fsindex.html?col=cam&qc=camPenalties Late to lab No extra time can be provided. No one can begin more than 1 hour after the start of lab Unexcused absence Failing grade Late lab report 1-2 days 15% off report 2-7 days late 25% off report >7 days late, 0 points, failing grade No lab report Failing grade Additional samples 20% off No goggles or labcoat 10 pts off, must go get them Improper attire must don proper attire before entering lab Afternoon lab ends at 4:50 pm, doors close at 5 pmPenalties Improper disposal of 5 pts off per offense - chemicals - waste - glass Don’t close containers 5 pts off per offense Leave equipment turned 5 pts off per offense on &/or plugged in Negligent spills 10 pts off per offense Messy workspace 5 pts off per offenseSAFETY GUIDELINES FOR WORKING IN A LABORATORY 1. Inform yourselves about safety measures in the lab. Everyone should know where the fire extinguishers, fire blankets, showers, and emergency exits are. 2. You may only work in your designated lab period. 3. Protect yourselves against potential injury. a. always wear safety goggles and lab coat b. no shorts, no sandals or open shoes c. rubber gloves when working with aggressive chemicals4. Never use an open flame in the vicinity of flammable solvents. Absolutely no smoking in the lab. SAFETY GUIDELINES FOR WORKING IN A LABORATORY 5. Carry all chemicals carefully and in front of you. 6. Eating and drinking are forbidden in the lab. 7. CAREFULLY READ Safety and