Chemistry 237 Structure and Synthesis Spring 2015 Lecture 1 January 20 2014 Why Experimental Organic Chemistry http images teamsugar com http www roadtrucker com http www energyinst org uk http www wikipedia org Why Organic Chemistry All pharmaceuticals aspirin ibuprofen penicillin prozac valium Plastics fabrics adhesives dyes refrigerants Electronics communications Energy gasoline catalysts solar cells Soaps detergents Nexium vs Prilosec Esomeprazole Chem 237 People Instructor Professor Steven C Zimmerman Teaching Assistants Section Chris Pattillo Daniel Holycross Robert Zhang AB1 AB4 AB1 AB4 AB2 AB5 Lab Manager Randy Wilkey 250 NL email pattill2 illinois edu holycro illinois edu gzhang32 illinois edu wilkey illinois edu If you drop the lab or changes sections notify Randy and the Chemistry Learning Center clc scs uiuc edu Chem237 Course Objectives Overall Objective to learn and apply the basic techniques and concepts of experimental organic chemistry Learn methods for isolation purification and characterization of compounds Learn methods for maintaining accurate records and for reporting experimental results Develop critical thinking and problemsolving skills with respect to organic chemistry Chem237 Course Content Reactions Acid catalyzed rearrangement Esterification Diels Alder Cycloaddition Hydride Reduction Etherification Claisen Schmidt aldol condensation Chem237 Course Content Methods for Purification Indentification recrystallization liquid liquid extraction distillation simple and fractional thin layer and column chromatography gas chromatography Spectroscopic Methods for Identification infrared spectroscopy NMR spectroscopy Chem237 Required Materials Syllabus Chemistry 237 Email copy and available on course website see IllinoisCompass2g Text Operational Organic Chemistry John W Lehman 4th Edition Pearson Prentice Hall 2009 Usage Card Purchase at Illini Union Bookstore Laboratory Goggles Must be approved goggles Eye glasses are not acceptable Labcoat Organic Chemistry Laboratory Notebook Chemical Education Resources Inc Recommended Materials Model Set good for all your organic courses Chem237 Tools for Success Textbook Read assigned reading every week Helpful hints and problem solving tips Useful to answer post lab questions Lectures Theory behind experiments and techniques Emphasis of important points in experiment Helpful hints and tips Attendance is required Chem237 Syllabus Tools for Success Experiment and Reading Schedule Safety Information How to perform basic techniques How to write your Pre lab and Lab Reports Experimental procedures Post lab questions will be posted later Web Illinois Compass Website Your user name and password are initially set to your Net ID CHEMNET tutorials recommended Discussion Board on course website Office hours Friday 4 5 pm Chem237 How to Succeed BE PREPARED Read the experiments in advance and come to lab ready to start do the Pre lab writeup Familiarize yourself with the background information provided in recommended reading WORK EFFICIENTLY Plan the optimal use of the laboratory period Multitasking is important Prepare for later steps during long reaction periods distillations etc Don t be afraid to ask questions Exams Exam dates Exam 1 Week of March 17 Exam 2 Week of April 28 Quiz 1 Never No Quizzes Quiz 2 Never No Quizzes Will cover material covered in lecture assigned reading and experiments Questions will be drawn from theory as well as practical material You are responsible for all assigned material for the exams Grading Scheme Lab Reports 375 TA Grade 50 Quiz 1 00 Quiz 2 00 Exam 1 100 Exam 2 100 Total Points for the Course 625 Distribution of Points per Experiment Expt 1 Expt 2 Expt 3 Expt 4 Expt 5 Expt 6 Expt 7 Isolation of BC Powder Banana Oil Conj Diene in Eucalyptus Oil NMR dry lab Acetylation of Ferrocene Unexpected Diol Reaction Multi step Synthesis Synthesis of Chalcone Total 400 40 40 85 85 85 40 Cheating No forms of cheating will be tolerated Copying of lab reports pre labs or notebooks will result in a failing grade for the course Faking data will result in a failing grade for the course Student ID s will be checked at exams For more info see the Student Code Article 1 Student Rights and Responsibilities Part 4 Academic Integrity at http www fs uiuc edu 1503 fsindex html col cam qc cam Penalties Late to lab No extra time can be provided No one can begin more than 1 hour after the start of lab Unexcused absence Failing grade Late lab report 1 2 days 15 off report 2 7 days late 25 off report 7 days late 0 points failing grade No lab report Failing grade Additional samples 20 off No goggles or labcoat 10 pts off must go get them Improper attire must don proper attire before entering lab Afternoon lab ends at 4 50 pm doors close at 5 pm Penalties Improper disposal of chemicals waste glass Don t close containers Leave equipment turned on or plugged in Negligent spills Messy workspace 5 pts off per offense 5 pts off per offense 5 pts off per offense 10 pts off per offense 5 pts off per offense SAFETY GUIDELINES FOR WORKING IN A LABORATORY 1 Inform yourselves about safety measures in the lab Everyone should know where the fire extinguishers fire blankets showers and emergency exits are 2 You may only work in your designated lab period 3 Protect yourselves against potential injury a always wear safety goggles and lab coat b no shorts no sandals or open shoes c rubber gloves when working with aggressive chemicals SAFETY GUIDELINES FOR WORKING IN A LABORATORY 4 Never use an open flame in the vicinity of flammable solvents Absolutely no smoking in the lab 5 Carry all chemicals carefully and in front of you 6 Eating and drinking are forbidden in the lab 7 CAREFULLY READ Safety and Emergency Facilities in your syllabus Standard Procedures for Each Lab Read the entire experiment in the syllabus and assigned reading in the textbook Prepare the PRELAB in your notebook Take the CHEMNET lesson optional Hand in your PRELAB to your TA at the start of the lab period yellow sheets or have notebook inspected Perform experiment record in lab notebook Collect and analyze data reach conclusions Submit online report with spectra and turn in samples in labeled vials turn in paper report This Week s Announcements Complete Check in and Safety Worksheet in lab Next Week Complete Parts 1 and 2 of Experiment 1 Prelab for all parts of Experiment 1 is due at the beginning of lab next week week of Jan 27 Do assigned reading for Experiment 1 Chem237