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MSU PSY 200 - Amnesia
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Psy 200 1st Edition Lecture 11 Current Lecture Amnesia- -Amnesia is a description of memory-Loss of memory that impacts all senses-Anterograde- partial or total loss of memory for events after neurological disturbance-Retrograde- loss of memory for events prior to neurological disturbance Retrograde-All memories are not lost, but more severe retrograde amnesia occurs with systemic diseases like Alzheimer’sAnterograde -Loss of memory for events that have occurred since the neurological disturbance (think of it as a learning deficit)Medial Temporal Lobe-Hippocampus, Amygdala, and surrounding cortex-e.g. hypoxia, herpes encephalitis-Anterograde amnesia shows no primacy effect-Recency effect in tact- primacy effect gone: no encoding benefit-Shift focus from localizing specific memories to focus on the study of memory processes-Emphasized that storage of memory could be distinct from formation of memory-Later work laid groundwork for studies of implicit memory-Learning without awareness (learn things but do not remember learning them)Summary of Hippocampal Amnesia-Normal Short Term Memory, poor Long Term Memory-Affects declarative memory without impairing non-declarative memory-Mainly anterograde amnesia-Some graded retrograde amnesiaDissociation of Declarative and Non- Declarative MemoryDo declarative and non-declarative memories result from operation of different systems? Or is there a single system and damage to this disrupts more difficult task of accessing information explicitly? These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.-This is a single dissociation problemHippocampal and Memory Acquisition -Medial temporal lobe region/hippocampus associated with acquisition of declarative memory: descriptive amount-Consolidation theory: hippocampus is part of network for developing associations between representations in different cortical areas. A process model.-Consolidation is the process by which memories are strengthened and stabilized, increasing resistance to interference and decay-Consolidation is an active process -Consolidation alters the memory representationSynaptic Consolidation -Long Term Potentiation (LTP)Systems Consolidation--Those that fire together, wire together Consolidation Theory of MTL and Memory Acquisition-Hippocampus is part of network for developing associates between representations in differentcortical areas-Accounts for:- role of MTL region in acquisition of new (declarative) memories-dissociation of retrograde and anterograde amnesiaConsolidation occurs in our sleepSleep and Declarative Memory-Sleep increases recall of paired associates-There is no significant change in performance after an equal interval of wakefulness -Implicit memory also improves with sleep-Sleep deprived patients did more poorly on a recognition test-Get a good nights


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MSU PSY 200 - Amnesia

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