BCHM 4116 1st Edition Lecture 2 Outline of Last Lecture I The Central Dogma II RNA World Outline of Current Lecture I Comparison of DNA RNA II Keto enolTautomeric Shifts Current Lecture I DNA vs RNA DNA RNA Bases A C G T Bases A C G U 3 hydroxyl group 2 hydroxyl group Genetic information Genetic information mRNA tRNA rRNA snRNA a Pyrimidine Cytosine Thymine Uracil Uracil replaces Thymine in RNA i One ring ii 6 membered aromatic ring b Purine Adenine Guanine i Two rings ii 5 membered imidazole ring fused with pyrimidine c N glycosidicbond links base to sugar in DNA RNA d Nucleoside sugar base e Nucleotide phosphate sugar base f Phosphodiesterbond links a nucleotide to another nucleotide II Keto enoltautomeric shift a To quantify DNA RNA use bases because bases are aromatic and have a strong absorption at 260 nm b Keto C O These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute c Enol C OH C C
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