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Robert Hooke (1665)
Used primitive microscope and looked at cork. Found it to be composed of "cells".
Van Lewenhook (1674)
Used magnifying glass and looked at pond water. Saw 1st microorganism.
Schlerden (1838) botanist Schwann (1899) zoologist
Examined tissues. Cells are building blocks of tissue. Led to cell theory.
Pasteur (1860)
Proved cell theory. Showed cells can only arise from pre-existing cells.
Cell Theory
1. All things are made of cells. 2. All cells came from other cells. 3. Cell is fundamental unit of life.
Glycolysis
Set of chemical reactions cells use to get energy.
Genetic Code
How to use information stored in DNA and RNA to make protein.
2 Major Kinds of Cells
1. Prokaryotic. 2. Eukaryotic.
Prokaryotic Cells
Small, simple, primitive cells. No nucleus. No membrane-bound organelles. Most are single celled organisms.
Eukaryotic Cells
Larger, more complex. Contain nucleus, cytoplasm, cytoskeleton, and various organelles. Often found in multicellular assemblies.
2 Types of Microscopes
1. Light microscope. 2. Electron microscope.
Light Microscope
17th century. Uses beams of light. Resolution limited by wavelength nature of light.
Electron Microscope
1930's. Uses beams of electrons. Greater magnification and resolution.
2 Types of Electron Microscopes
1. TEM-transmission electron microscope. 2. SEM-scanning electron microscope.
Plasma Membrane
Encloses cell. Separates inside from outside.
Cytoplasm
Surrounds nucleus. Contents of cell contained within plasma membrane (including organelles).
Cytosol
Contents of main cell compartment. Doesn't include organelles or nucleus.
Nucleus
Large structure that contains DNA. Organized into chromosomes. Enclosed by double membrane (nuclear envelope). Has nuclear pores that form openings in nuclear envelope.
Organelles
Discrete structures or subcompartments of eurkaryotic cells that are specialized to carry out specific functions. Enclosed by internal membranes.
Mitochondria
Present in almost all eukaryotic cell types. Several micrometers long. Enclosed by double membrane. Inner membrane is highly folded. Contain DNA.Reproduce by dividing.

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