Toxicology (exam 2)
5 Cards in this Set
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Explain the difference between morphological and functional effects.
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Morphological: generally irreversible gross and microscopic changes in the structures of the tissues
Functional: usually represent reversible changes in the functions of the target organ
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Define:
xenobiotic
toxin
toxicant
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1. a chemical that is exogenous to the normal metabolism of the animal or a foreign compound
2. a chemical from a plant/animal
3. a non-biological chemical
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What happened with the PCB contamination of the Great Lakes?
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Mink ranchers complained of reproductive failure in the late 1960s
ANS researchers discovered it was Great Lakes fish that were contaminated with polychlorinated biphenyls (PCB)
Mink are extremely sensitive to this
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What happened with the Michigan PBB Incident?
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Polybrominated biphenyl (flame retardant) was accidently added into animal feed in 1973
Resulted in the largest and most costly agricultural disaster in the country and contamination of over 90% of the population
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What prompted MSU's toxicology research programs?
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The Michigan PBB Incident
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Goats (exam 2)