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Homeostasis
tendency of an organism or a cell to regulate its internal conditions. Stabilize health and functioning.
Robert Hooke
First to discover and view cells in 1665.
Anton van Leeuwenhoek
First to observe microorganisms using a microscope of his own design in 1675. Described them as animalcules-little animals
Mitochondrion
Membrane-bound organelle in cytoplasm of most eukaryotic cells. Generates energy(ATP), stores calcium for cell signaling, generates heat, and mediates growth/deat
Plant Cell
Eukaryotic cells
Chloroplast
sunlight is converted to chemical energy during photosynthesis. Double membrane around exterior.
Central Vacuole
Lysosome like organelles in plant cells
Schleiden and Schwann
Cell Theory 1830s All living organisms are made up of cells Schwann=animals Schleiden=plants
Rudolf Virchow
1860s All cells come from pre-existing cells
Louie Pasteur
swan neck vessel to disprove the idea of spontaneous cell generation
Spontaneous Generation
The idea that cells spontaneously appear out of air.
Proton
Positively charged. Located in the nucleus
Neutron
No charge. Located in nucleus
Electron
Negatively charged. Located in electron orbital
Nucleus
Controls the cells function, contains the cells DNA, RNA comes out, contains genetic material
Element
A pure substance that cannot be broken down into any other substances by chemical or physical means
Atomic Mass
The average mass of all the isotopes of an element
Atomic Number
Number of protons in nucleus of an atom
Isotope
An atom with the same number of protons and a different number of neutrons from other atoms of the same element.
Elements common to life
Carbon, Oxygen, Hydrogen, Nitrogen, Phosphorus, Sulfur
Covalent Bond
Sharing electrons between elements
Ionic Bond
Transfer of electrons between elements
Ion
A particle that is electrically charged (positive or negative)
Cation
Positive charge=element loses electron
Anion
Negative charge=element gains an electron
Valence Shells
Outer most energy level containing active electrons
Reactants
Elements/Compounds that react with each other to produce a reaction or product
Products
Result of a chemical reaction
Exergonic Reaction
A spontaneous chemical reaction in which there is a net release of free energy
Endergonic Reaction
A non-spontaneous chemical reaction in which free energy is absorbed from the surroundings.
Electron Orbitals
Volumes of space surrounding the atomic nucleus where electrons are likely to be found
Morphine and Endorphins
Morphine-drug used to produce the same feelings the body naturally produces through endorphin hormone
Chromatin
Clusters of DNA, RNA, and proteins in the nucleus of a cell
Nucleolus
site where gene products are processed.
Nuclear Membrane
Double membrane which encloses the nucleus. Nuclear Envelope
Cytoplasm
all components of a cell, excluding the nucleus
Crystol
fluid portion between the plasma membrane and these organelles.
Ribosome
protein-manufacturing center in eukaryotic cells. Contains RNA and protein molecules.
Free Ribosome
ribosomes suspended in the cytosol that mostly synthesize proteins which dissolve in the cytosol and function there
Membrane associated ribosome
produce protein for the cell envelope and for secreation
Endoplasmic Reticulum
A system of membranes that is found in a cell's cytoplasm and that assists in the production, processing, and transport of proteins and in the production of lipids
Rough ER
Covered in ribosomes and is responsible for the synthesis and transport of proteins and glycoproteins.
Smooth ER
Does not have ribosomes attached to it. Responsible for producing lipids, steroids, regulation of calcium levels in muscle cells.
Lumen
interior of the rough ER. Site of protein folding
Golgi Apparatus
Consists of discrete flattened membranous sacs
Cis-Face
receiving end of the golgi apparatus
Cisternae
membranous sacs in the Golgi apparatus
Trans-face
the shipping face for transport vesicles leaving the golgi
Vesicle
A membrane bound sac that contains materials involved in transport of the cell.
Lysosome
recycling center which contains enzymes
Phagocytosis
A process in which some of the white blood cells destroy the invading microorganism and old cells.
Electronegativity
how strongly an element is attracting electrons.
Surface Tension
A measure of how difficult it is to stretch or break the surface of a liquid
Polar Molecule
A molecule that has electrically charged areas. WATER
Hydrogen Bonds
Very weak bonds; occurs when a hydrogen atom in one molecule is attracted to the electronegativity of another molecule
Polar Covalent Bond
results from unequal sharing of electrons
Polar Solvent
A dissolving liquid composed of polar molecules
Nonpolar Covalent Bond
results from equal sharing of electrons
Nonpolar Molecule
Molecule that shares electrons equally and does not have oppositely charged ends
Partial Charge
the unequal sharing of electrons which results in a slight negative or positive charge
Density of H20
1 g/mL (at 4 degrees C)
Specific Heat
The amount of energy that is needed to raise the temperature of 1 gram of a substance by 1° C.
Temperature Buffering
the amount of heat that must be absorbed or lost for 1g of a substance to change its temperature by 1 degree celcius
Heat of Vaporization
The amount of energy required for the liquid at its boiling point to become a gas.
Evaporation Cooling
the process in which the surface of an object becomes cooler during evaporation, owing to a change of the molecules with the greatest kinetic energy from the liquid to the gaseous state.
Cohesion
Attraction between molecules of the same substance
Adhesion
An attraction between molecules of different substances
pH
acidity level of a substance
Acid
Pulls in electrons=negative charge
Base
Pulls in protons=positive charge
Amphipathic Molecule
A molecule that has both a hydrophilic region and a hydrophobic region.
Micell
Amphipathic lipids with single hydrocarbon chains (fatty acids)
Bilayer
a layer that is two molecules thick
Phospholipid
major component of cell membrane higly amphipathic molecules form bilayer.
Phospholipid Bilayer
composes cell memebrane; amphipathic
Singer and Nicolson
Developed the fluid mosaic model 1972
Fluid Mosaic Model
A model that refers to how the lipid bilayer tends to act more like a liquid than a solid.
Hydrophobic
not attracted to water
Hydrocarbon
An organic molecule consisting only of carbon and hydrogen.
2nd Law of Thermodynamics
Molecules will naturally move down the concentration gradient
Entropy
(thermodynamics) a thermodynamic quantity representing the amount of energy in a system that is of disorder
Diffusion
Movement of materials from an area of high concentration to low concentration Water always moves to a higher concentration of molecules
Concentration Gradient
A region along which the density of a chemical substance increases or decreases.
Permeability
How easily liquid can move through an object
Semi-permeable membrane
a membrane (as a cell membrane) that allows some molecule to pass through but not others
Osmosis
Diffusion of water through a selectively permeable membrane
Hypertonic Solutions
Concentration of solutes is higher outside that inside, water moves out of the cell
Hypotonic Solutions
concentration of solutes is lower outside than inside, water will move into cell
Equilibrium State
the state in which the system (cell) is steady and constant
Facilitated Diffusion
natural movement down gradient through pre-shaped proteins in phospholipids bilayer,
Active Transport
Requires ATP, drives molecules/proteins up concentration gradients by changing shape of proteins
Sodium/Potassium Pump
Protein pump transports sodium of of cell and potassium into the cell 3 Na-2 K
Electrochemical Gradient
Ions move down a gradient toward the opposite charge
Adenosine Triphosphatase
A molecule present in all living cells and acting as an energy source for metabolic processes
Proton Gradient
a gradient formed by the difference in proton concentrations across a membrane
Fat
Lipid is a major class of macromolecule
Triglyceride
energy storage, insulation
Glycerol
A three-carbon alcohol to which fatty acids are covalently bonded to make fats and oils.
Fatty Acid
1. Stearic 2. Palmitic 3. Myristic 4. Oleic 5. Linoleic
Saturated Fat
Fully saturated with hydrogens. Single bonds
Unsaturated Fat
Double Carbon bonds, lessens the amount of hydrogen saturation.
Polyunsaturated Fat
A fatty acid that lacks 4 or more hydrogen atoms and have 2 or more double bonds between carbon atoms.
Cholesterol
A large, ring shaped lipid found in cell membranes. Cholesterol is the precursor for steroid hormones, and is used to manufacture bile salts.
Hormones
Chemical messengers, mostly those manufactured by the endocrine glands, that are produced in one tissue and affect another
Testosterone
A male hormone that stimulates the growth of genital and secondary sexual characteristics.
Estrogen
A class of hormones that produce female secondary sex characteristics and affect the menstrual cycle.
Cadherins
A member of an important class of cell adhesion molecules that requires extracellular calcium ions for its function.
Tight Junctions
Prevent things from slipping between cells that shouldn't be there. Seals them together
Desmosomes
Connect to cytoskeletons of cells
Gap Junctions
Pores that act as a channel between cells
Plasmodesmata
An open channel in the cell wall of plants through which strands of cytosol connect from adjacent cells
Dictyostelium
protist that can sense AMP(energy) and will move itself towards that energy
Amoeba
A type of protist characterized by great flexibility and the presence of pseudopodia.
Slug
created when multiple amoeba come together to move towards a signal
Fruiting Body
an organ specialized for producing spores
Autocrine Signaling
Cells release signals that affect themselves and nearby target cells
Paracrine Signaling
Cells secrete local chemical mediators that are quickly taken up, destroyed, or immobilized. The mediators act only on nearby cells.
Neurotransmitter
Chemical messengers that cross the synaptic gaps between neurons
Endocrine Signaling
signaling at a distance
Transduction
involves amplification of signal and control of the proteins production
G Protein
A GTP-binding protein that relays signals from a plasma membrane signal receptor, known as a G protein-coupled receptor, to other signal transduction proteins inside the cell.
Adenylyl Cyclase/cAMP
Stopping process to cooperate with neighbor
Phosphorylation Cascade
Kinase sends a phosphate to molecule
Lipid Soluble Steroid Hormones
Can enter target cell, bind to receptors inside the cell, and cause change in gene expression.
Transcription Factor
new mRNA produced=new genes=new proteins and enzymes for new functions
Change in Gene Expression
During an individual organisms' lifetime, this is most likely to help the organism respond properly to changes in its environment
Endomembrane System Functions
1. Synthesis of Proteins and transports into membranes, organelles, or out of cell 2. Metabolism and movements of lipids. 3. Detoxification of poisons

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