Front Back
What occurs during each wave of an ECG?
P Wave--> SA Node fires, Atria depolarize, Atria contract QRS Complex--> Ventricles depolarize, Ventricles contract, Atria repolarize T Wave--> Ventricles repolarize, Ventricles relax
Leukocytes
Structural Characteristics: only "true cells" (have nucleus, can reproduce) Function: Defense Classifications: Granular, Agranular
Further Classifications of Leukocytes
Granular: Neutrophils (acute infection), Basophils (histamine reaction), Eosinophils (allergic reaction--> parasitic infection) Agranular: Lymphocyte (B,T Cells--> immune response), Monocyte (chronic infection)
Thrombocytes
Structural Characteristics: not true cells; fragments of a large cell/megkaryocyte Function: Blood clotting
Disorders of Blood Clotting
Thrombi- a clot that develops and persists in an unbroken blood vessel Emboli- if the thrombus breaks away from the vessel wall and floats freely Anticoagulant Drugs Thrombocytopenia- # of circulating platelets is deficient Impaired Liver Function Hemophilias
Types of Hemophilias
Hemophilia A- no Factor VIII Hemophilia B- no Factor IX Hemophilia C- no Factor XI
Which types of Hemophilias are sex-linked and which aren't?
Hemophilia B and C are not sex-linked, while Hemophilia A is sex-linked
Blood Types Chart
Blood Types: A, B, O, AB Antigen: A, B, -, A/B Antibody: anti-B, anti-A, anti-A/anti-B, -
Which blood type is the universal donor?
O
Which blood type is the universal recipient and the rarest?
AB
Active Immunity
You have an exposure--> antibodies are made (ex: flu shot)
Passive Immunity
I'm going to give you the antibody
Chambers and Valves of the Heart
Chambers: Left Atrium, Right Atrium, Left Ventricle, Right Ventricle Valves: Atrioventricular (Tricuspid, Bicuspid), Semilunar (Pulmonary, Aortic)
Erythrocytes
Structural Characteristics: small size, biconcave shape, bound by plasma membrane, no nucleus Function: Transport oxygen Production: Takes place in red bone marrow Disorders: Anemia, Polycythemia
Functions of Blood
Transportation (because of blood) of nutrients, oxygen, carbon dioxide, hormones, enzymes Protection (WBC- foreign invaders, hemostasis- maintenance of blood--> blood clotting)
Extrinsic Pathway
Starts with tissue factor, which is released outside of the plasma in damaged tissue
Intrinsic Pathway
Starts when inactive Factor XII, which is in the plasma, is activated by coming into contact with a damaged blood vessel
Tunics of the Blood Vessels
(Inside--> Out) Tunica Intama, Tunica Media, Tunica Externa
Types of T-Cells
THelper, TCytotoxic (Killer), TSupressor
Blood Flow through the Heart
Vena Cava, Right Atrium, Tricuspid Valve, Right Ventricle, Pulmonary Semilunar Valve, Pulmonary Trunk, Pulmonary Arteries, Lungs, Pulmonary Veins, Left Atrium, Bicuspid Valve, Left Ventricle, Aortic Semilunar Valve, Aorta, Body
Coronary Circulation
the functional blood supply of the heart
Types of Pacemakers
On Demand (looks for SA node to fire), Constant
Pulmonary Circulation
The right side of the heart receives oxygen-poor blood from body tissues and then pumps this blood to the lungs to pick up oxygen and dispel carbon dioxide
Systemic Circulation
The left side of the heart receives the oxygenated blood returning from the lungs and pumps this blood throughout the body to supply oxygen and nutrients to body tissues
Electrical Conduction System of the Heart
SinoAtrial Node, Atrioventricular Node, Atrioventricular Bundle, R/L Bundle Branches, Purkinje Fibers
Differences found in Fetal Ciruculation
Foramen Ovale (flap between Right and Left Atrium), Ductus Arteriosis (Pulmonary Trunk and Aortic Arch), Umbilical Vein (brings nutrients and oxygen to baby), Umbilical Arteries (waste and carbon dioxide away from baby), Ductus Venosus (when Umbilical Vein enters baby)
Tetraology of Fallot
R=>L Shunt. PROVe. Pulmonary Stenosis, RVH, Overriding Aorta, VSD. RVH=> BOOT HEART. Early Cyanosis. Caused by anterior superior displacement of the infundibular septum.
3 Types of BLood Vessels
Capillaries (direct contact with tissue cells and serve cellular needs), Arteries (carry blood away from heart), Veins (carry blood to heart)
Overall Functions of Lymphatic System
To protect from foreign invasion
Organs and Tissues of Lymphatic System
Organs: Tonsils (gather and remove pathogens entering pharynx), Thymus (where lymphocytes mature), Spleen (blood cleansing), Peyer's Patches (similar to tonsils), Appendix (destroy bacteria, long-term immunity) Tissues: Diffuse Lymphoid Tissue and Lymphoid Follicles (ensure that lymphocy…
2 Types of Lymphocytes
T Cells, B Cells
T Cells
manage immune response, some directly attack and destroy infected cells
B Cells
protect the body by producing plasma cells (antibodies), memory cells
Immunity
resistance to disease
Nonspecific Resistance
External body membranes- skin and mucous membranes Internal defenses- antimicrobial proteins, phagocytes, fever
Cell-Mediated Immunity
type of immunity produced by T cells that attack infected or abnormal body cells
Humoral Immunity
specific immunity produced by B cells that produce antibodies that circulate in body fluids
Types of Immunoglobulins
IgG - most abundant, neutralizes bacterial toxins, source of maternal antibodies IgA - protects mucus membranes IgM - neutralizes organisms in the blood IgE - allergic reesponse, parasitic infection IgD - recognition of 'self' and 'foreign'
Types of Anemia
Hypovolumeic- low volume (Cause--> Trauma) Hemolytic- blood cells broke apart (Cause--> blood transfusion reactions)
Sickle Cell Anemia
Genetic; Beta cells have single protein difference that changes shape of hemoglobin/RBC, carries less oxygen; cells aren't flexible; African descent

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