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anatomy
the study of structure (1.1)
physiology
the study of function (1.1)
palpation
feeling a structure with the hands (1.1)
auscultation
listening to the internal sounds made by the body (1.1)
percussion
tapping the body to feel for abnormal resistance and listen for abnormal sounds (1.1)
dissection
the careful cutting and separation of tissues to reveal their relationships (1.1)
comparative anatomy
the study of more than one species in order to examine the structural similarities and differences and analyze evolutionary trends. (1.1)
exploratory surgery
opening the body and taking a look inside to see what is wrong (1.1)
medical imaging
methods of viewing the inside of the body without surgery (1.1) includes computed tomography (CT), positron emission tomography (PET), magnetic resonance imaging (MRI), sonography, radiography (Xray) (1.7)
radiology
the branch of medicine concerned with medical imaging (1.1)
gross anatomy
structures that can be seen with the naked eye (1.1)
histology
the branch of biology that studies the microscopic structure of animal or plant tissues (aka microscopic anatomy) (1.1)
Histopathology
the microscopic examination of tissues for signs of disease (1.1)
cytology
the study of the structure and function of individual cells (1.1)
ultrastructure
the fine detail--down to the molecular level as revealed by electron microscopes (1.1)
comparative physiology
the study of how different species have solved problems of life such as water balance, respiration, and reproduction; also the basis for the development of new drugs and medical procedures. (1.1)
Hippocrates
"father of medicine" ; he and his followers established a code of ethics for physicians--the Hippocratic Oath (1.2)
Andreas Vesalius
taught anatomy in Italy and was the first to use very detailed, lifelike art in his writing; he published the first atlas of anatomy (1.2)
William Harvey
remembered for his studies in blood circulation (1.2)
Robert Hook
improved the compound microscope and coined the term "cell" after viewing a slice of cork (1.2)
Antony von Leeuwenhoek
invented the simple microscope and discovered little animalcules in lake water (1.2)
Matthias Schleiden and Theodor Schwann
concluded that all organisms were composed of cells (1.2)
Francis Bacon and Rene Descartes
credited with putting science on the path to modernity by inventing new habits in scientific thought (1.3)
scientific method
certain habits of disciplined creativity, careful observation, logical thinking, and honest analysis of one's observations and conclusions (1.3)
inductive method
first described by Bacon, is a process of making numerous observations until one can draw generalizations and predictions from them (1.3)
hypothetico-deductive method
the way most physiological knowledge is obtained; an investigator begins by asking questions and formulating a hypothesis which leads to a prediction. Experimentation will either support the original hypothesis or point to a new one (1.3)
hypothesis
an educated speculation or possible answer to the question; a good hypotheses must be consistent with what is already known and capable of being tested and possibly falsified (1.3)
elements of experimental design
sample size, controls or control group, psychosomatic effects, experimenter bias, statistical testing (1.3)
sample size
the number of subjects used in a study (1.3)
controls / control goup
the control group subjects must be as much like the treatment group as possible except that they do not receive the treatment (1.3)
psychosomatic effects
effects of the subjects state of mind on his or her physiology; these are avoided by the use of placebos in experimental design (1.3)
experimenter bias
when conscious or unconscious, it is when the interpretation of results is effected based on desired results (1.3)
double-blind method
one in which neither the experimenter nor the subjects know which subjects are receiving the treatment and which are receiving a placebo; this technique prevents experimenter bias (1.3)
statistical testing
looking for statistically significant differences in data and then determining the probability that the data are correct (1.3)
peer review
a critical evaluation by other experts in the research field (1.3)
fact
information that can be independently verified by any trained person (1.3)
law of nature
a generalization about the predictable ways in which matter and energy behave (1.3)
theory
an explanatory statement derived from facts, laws, and confirmed hypothesis (1.3)
hierarchy of complexity: most complex to simplest
organism, organ system, organ, tissue, cell, organelle, macromolecule, molecule, atom (1.5)
organism
a single, complete individual (1.5)
organ system
a group of organs with a unique collective function; generally, the organs in an organ system are physically interconnected; the human body has 11 organ systems: integumentary, skeletal, muscular, nervous, endocrine, circulatory, lymphatic, respiratory, urinary, digestive, reproductive (1…
organ
a structure composed of two or more tissue types that work together to carry out a particular function
tissue
a mass of similar cells and cell products that forms a discrete region of an organ and performs specific function (1.5)
cell
the smallest units of an organism that carry out all of the basic functions of life; nothing simpler than a cell is considered alive; cells are enclosed by a plasma membrane (1.5)
are microscopic structures in a cell that carry out individual functions (1.5)
are microscopic structures in a cell that carry out individual functions (1.5)
macromolecules
the largest molecules--proteins, fats, DNA (1.5)
molecule
a particle composed of at least 2 atoms (1.5)
atom
the smallest particles with unique chemical identities. (1.5)
reductionism
the theory that large, complex systems can be understood by studying their simpler components; first espoused by Aristotle (1.5)
holism
theory complementary to reductionism which recognizes that an organism is often more than the sum of its parts (1.5)
anatomical variation
what we see in the book are structures common in about 70% of samples; there are many normal variations in anatomy (1.5)
characteristics of life
collection of properties that distinguish living things from non-living things: organization, cellular composition, metabolism, responsiveness, movement, homeostasis, development, reproduction, evolution (1.6)
organization
refers to the fact that living things display a higher degree of organization than non-living things (1.6)
cellular composition
living matter is always compartmentalized into one or more cells (1.6)
metabolism
consists of the sum of catabolism and anabolism; living things take in molecules from their environment and chemically change them into molecules that form their own structures, control their physiology, or provide them with energy. Metabolism requires excretion (1.6)
anabolism
relatively complex molecules are synthesized from simpler ones (1.6)
catabolism
relatively complex molecules are broken down into simpler ones (1.6)
excretion
the separation of wastes from the tissues and their elimination from the body (1.6)
responsiveness
the ability of an organism to sense and react to stimuli, also called irritability or excitability. (1.6)
homeostasis
homeo = "the same" and stas = "to place, stand, stay" so homeostasis is the ability to maintain internal stability; the body's ability to detect change, activate mechanisms that oppose it, and thereby maintain relatively stable internal conditions (1.6)
development
any change in form or function over the lifetime of an organism (1.6)
differentiation
the transformation of cells with no specialized function into cells that are committed to a specific task (1.6)
growth
an increase in size (1.6)
reproduction
the ability of living organisms to produce copies of themselves and pass their genes onto offspring (1.6)
evolution
genetic changes from generation to generation (1.6)
reference man
a healthy male, 22 years old, weighing 70 kg (154 lb), living at a mean ambient temperature of 20 degrees C, engaging in light physical activity, and consuming 2800 kcal per day (1.6)
reference woman
a healthy female, 22 years old, weighing 58 kg (128 lb), living at a mean ambient temperature of 20 degrees C, engaging in light physical activity, and consuming 2000 kcal per day (1.6)
dynamic equilibrium
balanced change around a set point, or average value, for a given variable (1.6)
negative feedback
a process in which the body senses a change and activates mechanisms that negate or reverse it; negative feedback is the key mechanism for maintaining health (1.6)
feedback loops
refers to the fact that feedback mechanisms alter the original changes that triggered them (1.6)
vasodilation
the widening of blood vessels which can help cool the body (1.6)
vasoconstriction
a narrowing of blood vessels which can help the body retain heat (1.6)
receptor
structure that senses a change in the body (1.6)
integrating center / control center
part of the body that processes the information gained by the receptor and "decides" what the appropriate response should be (1.6)
effector
the cell or organ that carries out the final corrective action (1.6)
positive feedback
a self-amplifying cycle in which a physiological change leads to an even greater change in the same direction--it is a way to produce rapid change (1.6)
Terminologia Anatomica
TA - codified in 1998 to standardize the terms of anatomy (1.7)
eponym
term coined from the name of a person (1.7)
acronym
word composed of the first letter, or first few letters, of a series of words (1.7)
anatomical position
the reference position in which: 1. feet are flat on floor and close together. 2. arms are at sides with palms directed forward, or supinated. 3. face is forward (A1).
supinated
rotated so that face is anterior, or forward (A1).
pronated
rotated so that face is posterior, or backward (A1).
sagittal plane
passes vertically through the body or organ and divides into a right and left side (A1)
midsagittal plane (median plane)
a sagittal plane that divides the body or organ into two equal halves (A1)
frontal plane (coronal plane)
a vertical plane that is perpendicular to the sagittal plane and divides the body into anterior [front] and posterior [back] portions (A1)
transverse plane
passes across the body or an organ perpendicular to its long axis and divides the body into superior [upper] and inferior [lower] portions (A1)
directional terms
describe the location of one structure relative to another structure; most terms list in opposite pairs: anterior/posterior, rostral/caudal, superior/inferior, medial/lateral, proximal/distal, ipsilateral/contralateral, superficial/deep (A1)
ventral
toward the front or belly (A1)
dorsal
toward the back or spine (A1)
anterior
toward the ventral side; belly side in humans (A1)
posterior
toward the dorsal side; back in humans (A1)
cephalic
toward the head or superior end (A1)
rostral
toward the forehead or nose (A1)
caudal
toward the tail or inferior end (A1)
superior
above (A1)
inferior
below (A1)
medial
toward the medial plane (A1)
lateral
away from the medial plane (A1)
proximal
closer to the point of attachment or origin (A1)
distal
further from the point of attachment or origin (A1)
ipsilaeral
on the same side of the body (A1)
contralateral
on the opposite side of the body (A1)
superficial
closer to the body surface (A1)
deep
farther from the body surface (A1)
dorsum
used to denote the upper surface of the foot and the back of the hand even though these areas do not face the same as the back in humans (but they do in cats) (A1)
axial region
consists of the head, neck (cervical region) and trunk (A1)
thoracic region
region of trunk above the diaphragm (A1)
abdominal region
region of trunk below the diaphragm; it is further subdivided into the right upper quadrant [RUQ], right lower quadrant [RLQ], left upper quadrant [LUQ], and left lower quadrant [LLQ]; can also be divided into nine regions the right hypochondriac region, the right lumbar region, the right…
appendicular region
consists of the upper and lower limbs (A1)
upper limbs
include the arms [brachial region], forearm [antebrachial region], wrist [carpal region], hand [manual region], and fingers [digits]. Strictly speaking, arm refers only to the upper part between the shoulder and the elbow. (A1)
lower limbs
include the thigh [femoral region], leg [crural region], ankle [tarsal region], foot [pedal region],and toes [digits]. Strictly speaking, leg refers only to the part between the knee and ankle. (A1)
segment of a limb
region between one joint and the next (A1)
body cavities
are lined with membranes and contain the internal organs called viscera (A1)
cranial cavity
enclosed by the cranium and contains the brain it is continuous with the vertebral cavity and lined with the meninges (A1)
vertebral cavity
enclosed by the vertebral column and contains the spinal cord; the vertebral cavity is continuous with the cranial cavity and lined with the meninges (A1)
thoracic cavity
during embryonic development the coelom (which becomes the diaphragm) forms the separation between the thoracic and abdominopelvic cavity; it is lined with a thin serous membrane; the thoracic cavity is divided by a thick wall called the mediastinum; the two pleural cavities contain the l…
abdominopelvic cavity
includes the abdominal cavity which is lined by the peritoneum and contains the digestive organs, spleen, kidneys and also the pelvic cavity which is lined with the peritoneum and contains the bladder, rectum, reproductive organs. The brim of the pelvis delineates the two cavities. (A1)
posterior mesentery
a translucent membrane which suspends the intestines from the posterior abdominal wall (A1)
mesocolon
the posterior mesentery of the large intestine (A1)
greater omentum
a fatty membrane which hangs like an apron from the inferolateral margin of the stomach and overlies the intestines (A1)
serosa
part of the visceral peritoneum which wraps around the internal organs and forms an outer layer (A1)
visceral peritoneum
consists of the mesenteries and the serosa (A1)
potential spaces
spaces between membranes which are normally pressed tightly together but which may contain fluid or other matter under unusual conditions (A1)
systems of protection, support, movement
integumentary system, skeletal system, muscular system (A1)
systems of internal communication and integration
nervous system, endocrine system (A1)
systems of fluid transport
circulatory system, lymphatic system (A1)
systems of input and output
respiratory system, urinary system, digestive system (A1)
systems of reproduction
male reproductive system, female reproductive system (A1)
integumentary system
organs: skin, hair, nails, cutaneous glands; functions: protection, water retention, thermoregulation, vit D synthesis, cutaneous sensation, nonverbal communication (A1)
skeletal system
organs: bones, cartilages, ligaments; functions: support, movement, protective enclosure of viscera, blood formation, mineral storage, electrolyte and acid-base balance (A1)
muscular system
organs: skeletal muscles; functions: movement, stability, communication, control of body openings, heat production (A1)
lymphatic system
organs: lymph nodes, lymphatic vessels, thymus, spleen, tonsils; function: recovery of excess tissue fluid, detection of pathogens, production of immune cells, defense against disease (A1)
respiratory system
organs: nose, pharynx, larynx, trachea, bronchi, lungs; function: absorption of oxygen, discharge of carbon dioxide, acid-base balance, speech (A1)
urinary system
organs: kidneys, ureters, urinary bladder, urethra; function: elimination of wastes, regulation of blood volume and pressure, stimulation of red blood cell formation, control of fluid, electrolyte and acid-base balance, detoxification (A1)
nervous system
organs: brain, spinal cord, nerves, ganglia; function: rapid internal communication, coordination, motor control and sensation (A1)
endocrine system
organs: pituitary gland, pineal gland, thyroid gland, parathyroid glands, thymus, adrenal glands, pancreas, testes, ovaries; function: hormone production, internal chemical communication and coordination (A1)
circulatory system
organs: heart, blood vessels; function: distribution of nutrients, oxygen, wastes, hormones, electrolytes, heat, immune cells, antibodies, fluid, electrolytes, and acid-base balance (A1)
digestive system
organs: teeth, tongue, salivary glands, esophagus, stomach, small and large intestines, liver, gallbladder, pancreas; function: nutrient breakdown and absorption. Liver functions include metabolism of carb, lipids, proteins, vitamins, and minerals; synthesis of plasma proteins, disposal …
male reproductive system
organs: testes, epididymides, spermatic ducts, seminal vesicles, prostate gland, bulbourethral glands, penis; function: production and delivery of sperm, secretion of sex hormones (A1)
female reproductive system
organs: ovaries, uterine tubes, uterus, vagina, mammary glands; function: production of eggs, site of fertilization and fetal development, fetal nourishment, birth, lactation, secretion of sex hormones (A1)
biochemistry
the study of molecules composing living organisms
element
the simplest form of matter to have unique chemical properties
6 major elements in humans
oxygen, nitrogen carbon, calcium hydrogen, phosphorus
trace elements
12 elements that are found in very small amounts in the body but they are very important--generally function as cofactors
minerals
inorganic elements that are extracted from the soil by plants and passed up the food chain to humans and other organisms. Minerals make up about 4% of the human body by weight
electrolytes
conduct electrical current in aqueous solution Main electrolytes in the body are Na+, Cl-, Mg2+, Ca2+, K+; they arrive as CaCl2, Na2HPO4, MgCl2, KCl, NaHCO3, NaCl
isotope
varieties of elements which differ from one another only by the number of neutrons in the nucleus; isotopes are not as stable and this instability leads to radioactivity--every element has at least one radioactive isotope
radioactivity
radioisotopes decay to stable isotopes and release radiation in the process; people are mildly radioactive; parent isotope decays to daughter isotope
high energy radiation
ejects electrons from atoms converting atoms to ions--aka ionizing radiation; can be quickly fatal in high doses; in low doses it is mutagenic and carcinogenic

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