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Amitotic
unable to divide
Nerve cell lifetime
over 100 years
Nuclei
clusters of cell bodies in CNS
Ganglia
cluster of cell bodies in PNS
Tracts
bundles of axons in CNS
Nerves
bundles of axons in PNS
Post synaptic cell
cell that revives a signal
Glial cell functions
nourishing, insulating and extracellular fluid removal
Resting potential
nontransmitting negative potential
Na/K pump
ATP used to pump 3Na out for 2K in
Which solute is more permeable
Potassium
Resting potential theory
Chemical gradient balances with electrical gradient
Which solute is most responsible for the nerve cell gradient
Potassium (-90mV)
Abundance of leak channels
Higher # of potassium leak channels
Gated ion channels
open or close in response to a stimulus(polerization or neurotransmitter)
Hyperpolarization
makes resting potential more negative, harder to create a signal
Depolarization
makes resting potential more positive, Easier to create a signal
Graded potential
potential strength changes around strength of stimuli
Voltage-gated ion channels
open and close based on change of membrane potential
-55mV
threshold of action potential
-70mV
average resting potential
-90mV
K+ only potential
+62mV
Na+ only potential
Resting State
all vGated channels closed
Inactivation Loop
blocks sodium from flowing into cell
Rising Phase
when threshold is crossed, Activation of Na+ gated channels begins unassisted
Why is E(Na) potntial not reached
B/c potassium begins to leave the cell
Why is resting potential overshot
Because Na channels are slow to respond
Why do action potentials travel unidirectionally
Because of the hyperpolarization "behind" the wave
Myelination
prevents signal leakage and allows saltatory conduction
jumping of signals from node to node on axon
jumping of signals from node to node on axon
Wider axons
faster signal propegation
Oligodendrocytes
mylin laying cells in CNS
Schwann Cells
mylin laying cells in PNS
Electrical Synapses
quickens cell to cell communication, seen in cardiac tissue
Chemical Synapses
neurotransmitters released by presynaptic cells
Ending neurotransmitter transmisson
uptake by presynaptic cell, metabolized by glial cells, metabolized by an enzyme, diffusion
EPSPs IPSPs
excitsory And inhibitory nurotrans signal
Neural Integration
addition of EPSPs can push a neuron over threshold

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