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Study Guide: Biopysch

Declarative Memory
Explicit or episodic Facts and events
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Nondeclarative Memory
Implicit Skills, habits, classical conditioning
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Encoding
Classifying/categorizing experiences
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Consolidation
Short term memory to long term memory
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Retrograde Amnesia
Retrograde amnesia is a form of amnesia where someone will be unable to recall events that occurred before the development of amnesia.
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Anterograde Amnesia
Anterograde amnesia is a loss of the ability to create memories after the event that caused the amnesia occurs.
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MAO inhibitors
Block destruction of excess monoamines in terminals.
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Tricyclic Antidepressants
Block reuptake of monoamines at the synapse.
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Monoamine Hypothesis
Depresion involves reduced activity at norepinephrine and serotonin synapses.
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Lithium Carbonate
Stabilizes neurotransmitter and receptor systems to prevent the large swings seen n manic-depressive cycling. Affects several neurotransmitter systems.
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Diathesis
A predisposition to become depressed.
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Diathesis Stress Model
Some indication that early exposure to stress increases the likelihood of developing depression in adulthood.
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Serotonin Transporter
Monoamine transporter protein that is responsible for reuptake of serotonin into the presynaptic neuron.
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Hyperfrontality
Excessive activity in prefrontal cortex and amygdala
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Positive Symptoms of Schizophrenia
Delusions (false beliefs, illogical thinking), hallucinations (false sensory perceptions), disorganized speech (incomprehensible language)
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Negative Symptoms of Schizophrenia
Social withdrawal, anhedonia, blunted affect (flattening of emotional expression), avolition (inability to initiate and sustain goal directed behavior), alogia (poverty of speech)
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Phenothiazines (i.e. chlorpromazine)
1st class of drugs used for treatment of schizophrenia. Tranquilizers that calmed surgical patients, did not treat schizophrenia.
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Dopamine Hypothesis
Schizophrenia involves excessive dopamine activity in the brain.
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Tardive Dyskinesia
Tremors and involuntary movements caused by blocking of dopamine receptors in the basal ganglia. Side effect of antipsychotic drugs used to treat schizophrenia.
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Atypical Antipsychotics (i.e. clozapine)
Target D2 receptors much less, so they produce motor problems only at much higher doses. Fewer side effects. Treats some negative symptoms.
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Hypofrontality
Reduced activity in the frontal lobes.
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Glutamate Theory
Reduced glutamate activity in the prefrontal cortex is involved in schizophrenia. Atypical antipsychotics increase glutamate levels.
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Sympathetic Adrenal Medullary Pathway
1. Activation of sympathetic nervous system 2. Stimulation of multiple organs by neurotransmitters (norepinephrine and epinephrine) 3. Stimulation of adrenal medulla (ACh) 4. Release epinephrine and norepinephrine into blood stream
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Antibodies
Produced by B cells of the immune system to recognize foreign antigens (invaders) and mark them for destruction.
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T-Cells
White blood cells that kill invaders.
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B-Cells
Fights intruders by producing antibodies that attack a particular cell type.
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Natural Killer Cells
Attack and destroy certain kinds of cancer cells and cells infected with virues. Less specific in their targets than T or B cells.
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Innate Immunity
No memory, anatomical barriers, phagocytes (macrophage), natural killer cells, inflammatory response (histamine release)
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Acquired Immunity
Protects against specific microorganisms, memory, acquired through having disease or immunization, T cells, B cells (antibodies)
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Dorsomedial Thalamus
Structure of the brain that plays a role in memory.
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Medial Temporal Lobe System
H.M. Symptoms: anterograde amnesia, mild retrograde amnesia, consolidatin disrupted, hippocampus & amygdala involved
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N.A.
Deficits: anterograde amnesia, encoding functions disrupted, dorsomedial thalamus involved.
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Korsakoff's Syndrome
Deficits: anterograde amnesia & remote memory loss, encoding & retrieval functions disrupted, brain areas involved are widespread, including frontal cortex and mammillary bodies of diencephalon.
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H.M.
Bilateral temporal lobe damage from surgery for epilepsy at 27 years old. Has difficulty learning and retaining new information (consolidation)
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