BIOL 209: Exam 4
17 Cards in this Set
Front | Back |
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Streptococci Virulence Factors
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– Protective capsule, hyaluronidase, streptokinase, pyrogenic exotoxin, streptolysin
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Streptococci Evasion mechanisms
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Molecular mimicry, encapsulation
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Staphylococcus host defense
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Epithelial barriers, phagocytosis, inflammatory response
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Staphylococcus evasion mechanisms
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Catalase and carotenoids inhibit ROS killing in phagosomes, protein A inhibits antibody opsonization
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Salmonella virulence factors
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Febrile/flagellar adhesion, enterotoxin, cytotoxin
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Salmonella host response
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Macrophage phagocytosis , adaptive immunity, T helper 1 cells (enhanced killing), antibody stop spread, direct complement mediated killing
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Salmonella immune evasion
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Phagocyte killing, alternate flagella forms
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Vibrio host defense
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Barrier function, neutralizing antibodies on secondary infection
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E. coli virulence factor
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Specific fimbrae (pili), anti-phagocytic capsule, exotoxins (enterotoxin/cytotoxins)
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E. coli host defense
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Clearance mechanisms on epithelial surfaces, antibodies to neutralize toxins, block adherence, phagocytic function for invasive strains
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E. coli evasion mechanisms
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Specific adherents mechanisms, variable surface antigens, anti-phagocytic capsule, intracellular growth
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Mycobacteria host response
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T-helper 1 cells release cytokines which stimulate killing ability of macrophages
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Treatment for mycobacteria
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Rifampin and isoniazid targets mycolic acid synthesis
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Trypanosomes host response
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Antibodies and complement proteins
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Treatment for Plasmodium
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Antimalarial drugs target processing of hemoglobin by pathogen
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Influenza host response
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Neutralizing antibodies and CTLs help control infection
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Influenza treatment
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Antiviral drugs amantadine and Tamiflu inhibit viral entry and release
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