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resting potential & components (5)
-70 mV in most cells, -60 mV in cardiac cells; high [Na+] in ECF, high [K+] in ICF, high [non-penetrating anions] in ICF
ampullary electroreceptors (2)
in almost all nonteleost fish, some teleosts, & many amphibis; respond to low freq electrical signals
passive electroreception; active electroreception
ability to detect extraneous electrical fields mostly for electrolocation; actively emit signals to receive feedback
tuberous electroreceptors (2)
more numerous than ampullary electroreceptors, on anterior surface in lateral line system to monitor changes in local transepidermal current flow
electrosensory lateral line lobe; marine fish electroreceptors vs freshwater fish
where electroreceptors terminate in brain; mainly ampullary & in long, low-resistance channels vs mainly tuberous & short
electrocytes (2)
thin cells stacked in columns & insulated w/ jelly to produce electric organ discharges, has a smooth & rough side w/ folds for ↑ SA
electrocyte potentials (2); 3 possible magnetoreceptor mechanisms
positive on both sides at rest, side that gets innervated becomes negative; magnetic induction in electroreceptors, magnetic minerals, & magnetochemical release
cryptochromes (2)
ancient blue-light receptors, light absorption → magnetically sensitive free radical rxns
4 types of ion channels; action potentials (2)
voltage gated, ligand gated, mechanically gated, thermally gated; rapid & brief, req a threshold potential for nondecremental response
graded potentials (4)
stronger trigger = stronger depolarization, occurs in specific cell membrane regions, spread by passive current flow, fade over distances
appearance of Na+ vs K+ channels; when Na+ channels close & K+ channels open
simpler ball & chain vs 2 gates that swing open & close; during peak b/n depolarization & repolarization
when K+ channels close; 5 neuron parts
after refractory period; cell body, dendrites for input, axon hillock (beginning of string), axon, & axon terminals
absolute vs relative refractory period; 2 synapse types; most common chemical class for neurotransmitters
depolarization & repolarization vs hyperpolization; electrical & chemical; amines
electrical synapse (4)
uncommon; electrical signal passes nearly unperturbed via gap junctions in direct contact; fast b/c of simplicity; good for escape responses, esp in inverts
chemical synapse (3)
common, synaptic cleft w/ neurotransmitters for indirect contact, slower & unidirectional
6 most common neurotransmitters
acetylcholine (ACH), dopamine (DA), epinephrine (EPI), norepinephrine (NE), serotonin (SE), & histamine (HA)
3 reqs for synapse to release
Ca2+ influx in synaptic knob, neurotransmitter exocytosis & diffusion across synapse, binding on ligand-gated receptors on postsynaptic neuron
excitation
brings postsynaptic membranes closer to an action potential by opening non-specific cation channels to cause excitatory postsynaptic potentials via depolarization
inhibition
pushes postsynaptic membranes farther fr an action potential by increasing K+ & Cl- permeability to cause hyperpolarization in inhibitory postsynaptic potentials
how body decides on excitation or inhibition (2); how long EPSPs & IPSPs cont
neurotransmitter & receptor combo will always have same response, time-based; as long as neurotransmitters are bound to receptor
slow synapses; neuromuscular junctions
mediate responses through 2nd messengers & neuromodulators; ea muscle cell has only 1
GPSP (3)
sum of EPSPs & IPSPs, can be temporal (same synapse firing quickly) or spatial (diff synapses firing simultaneously), determines whether or not action potential fires
centralization; 2 cnidarian nerve rings
nervous system moves into CNS & PNS; inside ring is for relaxed state, outside is for stress
bilateral symmetry; ganglia
introduces directionality ⇒ cephalization & centralization; similar neurons in a group
arthropod "brain"; expensive tissue hypothesis
actually a super ganglion; neural tissue is as expensive as gut tissue, so good brain = comfortable w/ behavioral changes to deal w/ lower quality food
maternal nrg hypothesis; internurons; somatic sensory nervous division
nrg amt Mom puts into raising offspring = brain size; integrator neurons only in CNS; for feeling in skin, body wall, & limbs
6 PNS divisions
sensory aka afferent (can be somatic or visceral) or motor aka efferent (can be somatic or autonomic, which can be sympathetic or parasympathetic)
somatic nervous system; autonomic nervous system (3)
motor innervation of skeletal muscles; motor innervation of smooth & cardiac muscle & glands
afferent vs efferent neurons; somatic motor neuron vs autonomic motor neuron
away fr receptor vs towards receptor; myelinated along entire axon vs myelinated only preganglion
saliva, liver, & bladder in sympathetic & parasympathetic
sym: saliva flow & bladder contraction inhibited, glycogen → glucose; para: saliva flow, bile production, & bladder contraction stim,
4 glial cells; 2 cells that provide myelin
astrocytes, microglia, oligodendroglia, & schwann cells; oligodendroglia & schwann cells
astrocytes (4)
provide neuron support by transporting nutrients, securing neurons in place, digesting dead neurons, & regulating extracellular space's content
microglia; enteric nervous system
CNS macrophages that digest dead neuron, in walls of GI system & can function w/o help fr other nervous systems
autonomic vs somatic neurotransmitters; BBB
can use both ACH & NE vs can only use ACH; tight junctions that allow water, some gases, & lipophilic molecules via diffusion & glucose & AA via transport
cerebrospinal fluid
clear fluid in brain & spine to cushion & provide immunological protection & blood flow regulation
reln b/n brain & body wt; what concussions affect; statocysts
logarithmic; neurotransmitters & not neurons themselves; mechanoreceptors w/ granulolymph for orientation
6 parts of brain stem fr top to bottom
thalamus, optic tract linked to thalamus that wraps around midbrain, pons, medulla oblongata, spinal cord
cerebellum; frontal lobe (3)
lump at base of cerebrum that regulates balance & fine motor skills; controls intellectual ability, personality, & emotion
parietal lobe, occipital lobe, temporal lobe (2 ea)
Middle of cerebrum, controls literacy & spatial relnships. Back of cerebrum, controls sight. Cerebrum sides, controls memory, speech, & comprehension
3 sensory receptor types
interoceptors (internal enviro), proprioceptors (body position & movement), & exteroceptor (external enviro)
vestibular system
in vestibulum of inner ear to contribute to balance, spatial orientation, & movemen
what 5 primary tastes are driven by; 3 types of nociceptors
Salty by Na+ influx; sour by H+ influx; sweet, bitter, & umami by GPCRs. mechanical, thermal, & polymodal
heat receptors (5)
aka vanilloid, TRPV3 activates above 33°C, TRPV1 activates above 42°C & fr capsaicin & garlic, TRPV2 activates above 52°C, TRPV4 activates below 33°C
cold receptors (2)
TRPA1 open near freezing & is mod in pit vipers & reponds to wasabi & cinnamon, TRPM8 opens fr 8-28°C & responds to menthol
fast vs slow pain pathway
uses myelinated nerve fibers, localized, brief; uses unmyelinated nerve fibers, general, activated by chemicals
prostaglandins; 3 endogenous opiates
released by dmged tissue to ↑ nociceptor sensitivity; endorphins, enkephalins, & dynorphins to suppress pain
3 hormone types
peptides (hydrophilic & derived fr AAs), amines (hydrophilic & derived fr tyrosine), & steroids (lipophilic & derived fr cholesterol)
hypothalamus (4)
lower central part of brain that regulates satiety, metabolism, body temp, & pituitary gland
anterior pituitary gland (6)
makes GH, TSH, adrenocorticotropic hormone (ACTH for corticosteroid production), LH, FSH, & prolactin
posterior pituitary gland; thyroid gland
releases ADH & oxytocin; regulated by pituitary gland to regulate metabolism & children's brain growth

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