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GxE
effects of genes depends on the environment experienced
Passive GxE
experienced environment influenced by parent's genes and passively experienced by child
Evocative GxE
child's genotype evokes environmental influences
Active GxE
genotyped influences environment a person seeks
Epigenetics
control of gene expression by the environment and microenvironments
Transcription Factor/ Promoter Region
-influence how a gene is expressed
Why does epigenetics influence Developmental Psychology?
-mandated to give an idea of what can change - how to change spiral/cycle
Michael Meaney
rats being licked --> stress response
Prenatal
before birth
Perinatal
during birth
Postnatal
after birth
Ovulation Period
- can conceive 5 days leading up to and day of ovulation
Percentage of first tries
-15%- 20% pregnant first try
1st 6 months
-70% conceive
Infertility
unsuccessful attempts for 12 months
Reasons for Infertility
Age Medications Rejected fetus Immotility of Sperm Chemicals/ Radiation Shape of uterus/ovarian cysts Low sperm count Improperly implanting egg No/irregular ovulation
Mother stages of Pregnancy
First/Second/Third Trimester
First Trimester
morning sickness rise in hormones evolutionary protection
Second Trimester
Quickening (first fetal movements)
Third Trimester
lots of growth and movement, weight
Prenatal for Child
Germinal Period, Embryonic Period, Fetal Period
Germinal Period
Zygote-Blastocyst-Implantation
Implantation
Blastocyst implants to uterine wall 50% succeed Immune system attacks, chromosomal abnormalities, thin uterine lining
Embryonic Period
Organogenesis Endoderm, Mesoderm, Ectoderm Majority of miscarriages.
Organogenesis
every major organ formed develops in order of importance for survival
Endoderm
internal organs (stomach, liver, etc)
Mesoderm
muscles, arteries, bones
Ectoderm
central nervous system, eyes, skin
Support System
Amniotic Sac, Placenta, Umbilical Cord
Amniotic Sac
fluid filled sac temperature constant, protective
Placenta
-supplies oxygen/nutrients -removes waste/carbon dioxide
Umbilical cord
blood vessesl connecting embryo and placenta
Folic Acid
-important for full development -neural tube defect (incomplete inclosure)
Fetal Period
9th week-birth bodily structures complete central nervous develops 23-25 weeks is viability survival possible, not guaranteed.
Bodily structures completion
- muscular development -bone formation -weight gain
Fetal Hearing
fetus can distinguish between sounds can ring a bell to wake fetus can diagnose congenital deafness
Prenatal Chemosensation
distinguish sweet/bitter mother's odor preferred at birth
Teratogens
any substance in the environment that can cause physical malformations during prenatal development
Variables in Teratogens
critical periods/timing dosage+duration genetic makeup environment
Thalidomide
prescribed to help morning sickness stunted limb growth Thoms Quasthoff
Nicotine/Tobacco
ADHD Conception down, miscarriage up Premature birth/ placenta issues Low birth weight circulatory restriction= slow growth obesity long run
Alcohol
Fetal Alcohol Syndrome Can cross placenta Amount depends on metabolism. Binge drinking factor "Phenotype" physical appearance emotional regulation, ADHD, behavior issues
Cocaine
cross barrier preterm delivery placental problems Neonatal withdrawal Intrauterine, neonatal, and SIDS
Rubuella (German Measles)
common in children, dangerous in fetus Miscarriage/death blind, deaf, heart defects timing important- organogenesis
AIDS
can be translated pre, peri, post virus can cross placenta blood exchange at birth during breast feeding no treatment- 15-30% chance
Radiation/Pollution
ex. mercury in fish, pesticides X rays
Maternal age- teenage
not mentally/physically mature prenatal care down poor nutrition premature double mortality
Maternal age- Advanced (35+)
abnormal genetic material higher egg/in vitro=multiples more substance exposure older father chronic diseases (gestational diabetes, hyptertension, arthritis)
Cephalocaudal
head to tail
Proximodistal
Center outward internal organs first
Orthogenetic
basic and undifferentiated to specialized
order of importance
important develops first
Newborn brain
25% of adult axons not mylenated
Young brain
2 years= 75% 1 year= 60% nutrition 3 years = 80% of connections
Synaptogenesis
formation of synapses, prominent birth to 3 years
Synaptic Pruning
Significant at 10 years
Enriched Environments
brain size up number of synapses up activity of neurotransmitters up
Plasticity
responsive to an individual's experiences and can develop accordingly ex. language acquisition
Reflexes
many needed at birth, can be an issue if present later on voluntary behavior replaces help newborn respond to environment
Diagnostic
absence or presence important can indicate lower brain development, chromosomal abnormalities
Classification
First Essential v Nonessential Second Approach v Avoidance
Reflexes (list)
rooting sucking grasping stepping moro babinski
Moro Reflex
disappears 5-6 MO absent or weak response indicates serious disturbances of central nervous system
Babinski
bottom of foot stroked, big toe in, others out at 2years- brain damage
Reaching and Grasping
grasping reflex Pre-reaching (swipe) Direct reaching (3 mo) Directed Reaching + Grasping (5 mo) Picking w 2 fingers (6 to 9 mo) Pincer grasp (11 mo) Pointing (13 mo) (basic communication)
Locomotion
Stepping reflex, kicking (dis- 2 to 3mo) head control (3-4 mo) rolling over (4-5 mo) sitting alone (6 to 7 mo) crawling (8 to 9 mo) standing, cruising (9 to 12 mo) Walk (12 mo) Run (18 mo) Jumping/ hopping (2-3 years)

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