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IPHY 2420: FINAL

Pine Ridge Demographics
Oglala Lakota (Sioux) Reservation southwest corner of South Dakota (8th largest res in nation) larger than delaware/rhode island combined not good for farming (done on purpose, told to go there) different rules, taxes, cops, courts in these nations
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Pine Ridge Social Issues
Poorest res in the country (median income: $3,100) Unemployment rate 83-85% (casino main source of income, not outsiders --> don't drive to it) School dropout rate 70% (school funding by the US Bureau of Education in the bottom 10%) Housing is poor (average 17 people per home, small trailers hold 30 people, BLACK MOLD)
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Pine Ridge Nutritional Choices
Commodities Program donates extra food to Indian reservations, schools, prison food tell them how many people you have, they give you a box, take whatever you get Sioux Nation Grocery Store only grocery store on the res no public transportation
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Pine Ridge Health Conditions
-Diabetes rates 8x higher -Infant mortality rates 3x higher (mold?) -Cervical cancer 5x higher -Blood quantum -50% of adults have addiction issues (has to be dry) -life expectancy: males = 48, females= 52
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Pine Ridges Health Conditions
Highest rates of early childhood cavities dental plaque buildup leads to peridontal disease not taught to brush their teeth 50% access to fluoride water smokeless tobacco
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Dental Plaque
a biofilm that forms on the surface of teeth microorganisms consume carbs and convert them to acid causes demineralization and inflammation of gums
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CVD plaque
composition: cholesterol cause: poor diet result: CVD/ high blood pressure
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Pine Ridge and Dental Plaque
Native Americans show higher concentrations of decay causing microorganisms at early ages Current theory: malnutrition during first trimester of pregnancy
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Native Americans and bottleneck
Only the ones that survived diseases became the population today Societal factor: nutrition, education, health care High baseline of: pro-inflammatores (high immunity) IL-6: interlucken 6 Could account for early onset of dental problems Early onset dental problems could help cause severe CVD later in life
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Pro-inflammatories: high immunity but
Thrifty gene hypothesis (April months) periods of starvation in April run out of food but cant grow food (too cold) benefits you to be as large as possible if you have the thrifty gene you can make it through the starvation month because you hold onto fat but causes type 2 diabetes/ hypertension
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IL-6: interlucken 6
is everything okay? frantic checking for disease as soon as they are exposed to disease they react very quickly, if you have high IL-6 levels you are prone to Type 2 Diabetes
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TAKE HOME OF THE LECTURE: CHRONIC INFLAMMATION
societal factors/genetics: IL-6, health care/blood quantum, Education (no good teachers/resources), Access to food, Commodities (no choice), Transportation, Housing/black mold, Addiction, Thrifty gene, Addiction, Thrifty gene, Income
 Malnutrition during pregnancy: how they cook meal Dental plaque, proinflammatories, CVD
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Premiums
how much you pay yearly (paycheck deduction)
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Deductibles
how much you pay before insurance starts paying ($10,000)
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Co-payments
how much you pay each time you see the doctor or specialist or go to the ER
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Health savings accounts
a savings account that can only be used to pay medical expenses out of pocket
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Pre-existing condition
a documented medical condition sometimes will not cover you because you will be expensive
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Affordable Care Act
before 2010, 50 mil americans did not have any kind of health insurance NOT a gov't run healthcare system set up by the gov't run by private insurance ACA built off of current public and private insurance (patchwork solution) before ACA, if you worked less than 40 hours they did not give you insurance
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3 key features of ACA
new customer protections improving quality and lowering costs increasing access to affordable care
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New customer protections
Prohibits discrimination due to pre-existing conditions or gender - cannot refuse or renew policies, cannot charge higher rates based on health status (smoker) establishes customer assistance programs in the states -states can apply for federal grants to help consumers -actual person (federal employees) there to help you
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Improving quality and lowering costs
making health care more affordable tax credits are available to help lower the cost of their insurance** Establishing the health insurance marketplace (high transparent and competitive market) if an employer does not offer individual insurance able to buy directly from marketplace***
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Increasing access to Medicaid
qualifications for Medicaid expanded to 133% of the poverty level states will receive 100% federal to support expanding covering
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Extending coverage to young adults
under the law, young adults will be allowed to stay on their parents' health plan until age 26 used to be 19
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CASE STUDY: Diabetes
Uninsured male, 67, Type 1 diabetes the annual costs for diabetes is expensive Under ACA, diabetes is categorized as "pre-existing condition" PCIP: pre-existing condition insurance plan: provides insurance to U.S. citizens with a pre-existing condition who have been uninsured for over 6 moths
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PCIP: Pre-existing condition insurance plan
covers major medical and prescription drug expenses, hospital care, preventative care, and annual physicals PCIP users required to pay any premiums, deductibles, copayments eligible for Medicare, which can cover the remainder bandages, wound healing, extensive stays
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CASE STUDY: Pneumonia
Female, 25, pneumonia remain covered until age 26 if parents are uninsured: the daughter qualifies for Medicaid id she is unemployed, or she can purchase individual health care
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Coverage options 26-36
ACA relies on this age group to buy into the Marketplace insurance plans to help pay for the increased pool of insurance Americans Options: public coverage: provided by gov't, based on low income, age, disability, etc private coverage: private company, more access with ACA, limits on costs
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ACA Summary
Before ACA, 50 mil Americans could not afford health care, so they were left uninsured risk for the country, population risks bankruptcy if they fall ill discourages healthy lifestyle because population ignores illness/have chronic diseases (preventative vs. reactive) Pool of insured Americans is increased patches Allows more people to qualify for health coverage
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Most nutrient dense dessert
pumpkin pie
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Highest number of calorie appetizers
o Texas cheese fries with chili and ranch 2120 calories. 70 o Hot spinach and artichoke dip with chips 1610. o Boneless Buffalo wings with blue cheese 1490. o Loaded baked potato soup 410.
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Highest number of protein appetizers
o Texas cheese fries with chili and ranch 97. o Hot spinach and artichoke dip with chips 33. o Boneless Buffalo wings with blue cheese 76. o Loaded baked potato soup 15.
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IHOP high sodium
ham has heavy salt content
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High Saturated fat
grilled cheese sandwich- butter and cheese
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Epigenetic Generations
Mother: 1st generation Fetus: 2nd generation Reproductive cells: 3rd generation -if mom is smoking all 3 generations are affected YOUR FOOD CHOICES INFLUENCE WHAT GENES ARE TURNED ON, INFLUENCES HOW YOU AGE, WHAT DISEASE YOU GET
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Epigenome
protein and other molecules that regulate expression of genes turning genes on and off inherited or altered Regulation: Histones methyl groups
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Bioactive food components and gene expression
Bioactive food component (nutrient or phytochemical) gene expression activated or silenced protein synthesis increased or decreased changes in cell and tissue functioning disease prevention or progression
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Epigenetics
future generation effects embryonic development health implications bioactive constituents in whole foods
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Dutch Hunger winter
germans cut off food supplies to the netherlands in WW2 calories reduced to 500-1000 per person women who were pregnant during the time had babies with altered genetics (more prone to obesity and heart disease than their siblings before or after famine)
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TEST QUESTION IFG2 gene is..
the gene that is altered during starvation event
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Hunger in America
Americans don't like to talk about it "wealthiest country in the world" 1968 video Hunger in America (1st time Americans heard about it) 1:6 Americans vs 1:20 Europeans
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Who are the hungry? 10 years ago and today?
the working poor unemployed/ under-employed migrant farm workers (how much they pick) undocumented workers (can be let go) elderly (lost their wages, on social security) homeless children
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Who are the hungry? Today
married clothed housed a bit overweight working people (wages have declined) 1/3 of families who are hungry have at least 1 working adult- typically a full time job
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Food Insecurity
any household where during the previous year, people did not have enough to eat occurs whenever the availability of nutritionally adequate and safe food, or the ability to acquire acceptable foods in SOCIALLY ACCEPTABLE WAYS (dumpster diving, stealing), is limited or uncertain
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Pattern of malnutrition
worry about how to get enough food stretch resources, more money to other expenses and less to food quality and variety of the diet decreases adults eat less and less children eat less and less
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Food insecurity questionair
light food insecurity: didnt have enough money to get more food when food went bad moderate food insecurity: people did not eat severe food insecurity: children did not eat for a whole day (severe because parents feed their children first)
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US programs to address food insecurity
SNAP, WIC National school lunch program, school breakfast program, special milk program food distribution on indian reservation elderly nutrition program summer food service program disaster feeding program
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Private sources of food/food distribution
soup kitchens religious organizations (give you a meal and a bus ticket to get to the next church) food pantries (donated food) home delivery of meals (meals on wheels)
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Three step burden
Poverty, hunger, malnutrition limits access to medical care discouraged education and personal advancement (person is working day to day to find food) change in time scale
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Poverty-obesity paradox
overconsumption of calories/malnutrition food quality is low crop subsidies (food is cheaper) overeating when food is available physiological changes (thrifty gene)
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Food deserts
Urban neighborhoods and rural towns without ready access to fresh, healthy, and affordable food instead of supermarkets and grocery stores, these communities may have no food access or are served only by fast food restaurants
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Effects of hunger
malnutrition- iron/zinc/protein/antioxidants veggies only available when SNAP $ available/ 1st of the month stress from unexpected bills ADHD or Hunger? inability to focus in school hoarding or stealing eating quickly when food is available
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Solutions
Aquaponics: grow plants and underneath is fish, feces used as fertilizer food co-ops sponsorship boxes big store grocery delivery mobile produce trucks in food deserts
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Epidemiology: risk assessment for obesity
higher rates for women than men all racial and ethnic groups vulnerable rapid rise exceeds genetics childhood obesity rates concerning
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Modifiable risk factors: DIETARY
increased caloric intake from beverages shift to more saturated and processed fats decreased intake of fiber portion sizes simple sugars
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Modifiable risk factors: LIFESTYLE
exposure to chemicals that act as endocrine disruptors indoor living: less sun/decreased physical activity/ altered circadian rhythm amount of processed foods eaten
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Modifiable risk factors: physiological
stress forfeiting lactation: lose protection against obesity for mother and infant stressors in the fetal environmental that increase obesity risk-gestational diabetes/epigenetics
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Obesity exacerbating conditions: makes obesity worse
amount of time sitting per day asthma (steroids, interferes with exercise) depression/emotional eating, eating disorders (holds onto fat) sleep disturbance (sleep apnea, restless leg) type 2 diabetes eating to regulate insulin, cravings, edema, muscle atrophy
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Other obesity issues
sex hormone imbalance (obesigenic fertility medications: ironically harder to become pregnant, pregnancy, menstruation, obesity can exacerbate hormone imbalances) subclinical hypothyroidism (1/10 americans are low, causes slow metabolism time of year born (winter= hold onto fat)
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Gut microbiota
a family of gut bacteria that help people say thing H. pylori: ulcers, regulates ghrelin, hormone that increases appetite transfer gut biota 2/3 of people antibiotics industrial farming: we injest antibiotics that are injected into cows.... kils h. pylori
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How to lose weight
more fiber and water lean proteins less saturated fat reducing calories increasing activity
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Bariatric surgery
gastric banding: put a band to trick the stomach stretch receptors to think you are fuller faster cheapest, easiest, least successful gastric bypass: redirect passage straight to small intestine, stomach floats around most extreme, highest success sleeve gastrectomy: cutting the stomach to 1/10 the normal size (permanent)
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Providing protein for an expanding human population
increasing demand for protein
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Aquaculture
the world now produces more farmed fish than beef population and income growth seafood has a heart healthy reputation
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commercial farmed fish
global catch of wild fish stagnant we need more protein but not from wild fish concerns about feedlot industry: can pollute locally, waste from fish is small area can cause significant nitrogen toxicity
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Blue revolution
90% of farmed fish and seafood are from Asia tropical mangroves destroyed for shrimp farms agricultural pollution- nitrogen/ phosphorus/ dead fish densitites- antibiotics and pesticides banned for use in u.s., u.s. imports 90% of its seafood, 2% inspected, found numerous banned susbstances
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Blue revolution cont.
tilapia, carp, cat fish: fast growing, most frequently farmed density and intensification feeding fish to grow quickly: cheapest=cornmeal=omega 6=pro-inflammatory only get omega 3 (heart healthy) when fed stream insects feeding fish to fish
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Atlantic salmon industry
densely packed pens in oceans norway, scotland, chile, patagonia growing atlantic salmon feces are naturally taken away by currents food naturually brought it
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Open water vs. tanks
Open water: parasites, pollution, disease cant control situation dont have to worry about oxygen, temp, nitrogen, feeding, cleaning Tank: have to be near huge sources of water, $$$$ can control situation
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Land farming
dig a ditch and fill it with fish always have to worry about nitrogen
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Why fish?
fish need fewer calories to create a pound of food than other species**** cold blooded (dont spend energy/ burning fat to keep warm) buoyant environment (not working against gravity)
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Aquaponics
use nitrogen as link between aquatic and terrestrial system symbiotic interaction (fish produces waste -> microbes and worms convert waste to fertilization for plants -> plants filter water that return to the fish) scale is the problem
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Insects as food source
1900 edible insects on earth 2 billion people eat them daily either raw or cooked only west still has the "ick" factor insects convert protein more efficiently than any other anima;
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Entomophagy
consumption of insects as food new united nations reports urges countries to eat insects
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Case for insects
rising cost of animal protein environmental pressures (cows belch methane that directly break down green house gases) population growth efficient conversion of energy increased demand for protein among the middle class****
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Case studies in insect nutrition
-mealworms: protein, mineral and vitamin content similar to fish -grasshoppers: as much protein as beef but less fat -beetles: more protein than other insects, NA ate them like popcorn over coals -butterflies/moths: pupal stages, full of protein and iron so eaten by children and pregnant women -ants: 100g= 14g protein (more than eggs), 48g of calcium, + iron
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pro insects
less water/ water pollution no methane no land use
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con insects
cleanliness (cooking) spoilage (if pupae die they spoil quickly) pesticides and insecticides toxicity low levels of toxicity eating a lot could be toxic
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other protein sources
soybeans tofu/tempeh quinoa beans/lentils not complete proteins by themselves but can be added to other things seitan: wheat meat
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Cow milk
pros: good source of protein, vitamin A, calcium; most variety in natural vitamins and minerals cons: fat content (your choice) nutrients from cow milk may be more bioavailable than non-dairy alternatives
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Soy milk
what it is: soaked soybeans and water pros: low in cholesterol, good source of vitamins (A,D,B12, folate, riboflavin) and minerals (Mg, P, K, Ca) cons: common allergen; possible hormonal effects due to phytoestrogens, often contains GMOs
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Almond Milk
what it is: ground almonds, water pros: low in calories, fat, and cholesterol; good source of fiber, vitamins (A, D, E) and minerals (Ca, Mg, Mn) cons: high in sodium, low in protein, common allergen
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Rice milk
what it is: boiled brown rice, rice starch, water pros: low in sat fat and cholesterol when fortified good source of vitamins (folate, vitamin D, vitamin B12) and minerals (Ca, P) cons: very low in protein and fat (essentially all carbohydrates)
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Coconut milk
what it is: coconut meat grated into water pros: low in cholesterol and sodium, good source of manganese and iron, vitamin B12 cons: very high in sat fat (MAYBE NOT A BAD THING?), little calcium and vitamin D
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Hemp Milk
what it is: hemp seeds soaked and ground into water pros: low in cholesterol, sodium, sat fat; good source of vitamins (A, E, D, B12, riboflavin) and minerals (Ca, Mg, P) cons: lower quality protein
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TEST QUESTION: WHICH TWO MILKS CONTAIN THE MOST COMMON ALLERGEN
almond and soy
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meal replacements
soylent ambronite meal squares
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Soylent
...
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Ambronite
the same as soylent but better organic, whole foods products, healthier, more expensive
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Mealsquare
...
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