WCU BIOL 306 - Hasimoto's Disease (7 pages)

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Hasimoto's Disease

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Dakota Parris Biology 111 April 29 2013 Hashimoto s Disease Hashimoto s thyroiditis also known as chronic lymphocytic thyroiditis is an autoimmune disease one of a large group of diseases characterized by abnormal functioning of the immune system that causes the body s immune system to produce antibodies against it s own tissues In Hashimoto s antibodies view the thyroid a small butterfly shaped gland located at the base of the neck as a foreigner and continue to attack disrupting the gland s ability to produce thyroid hormone that regulates body temperature and the body s ability to metabolize oxygen and food into energy Its autoimmune component along with symptoms that often mimic the symptoms of other diseases make Hashimoto s a disease difficult to diagnose and treat Regarding it s unusual name the disease was discovered and researched by Hakaru Hashimoto a Japanese scientist who wanted to enter the medical field but was unsure what area of medicine interested him most He became interested in thyroid tissue while working in a surgical department during the early part of the twentieth century He started to research this new unknown disease Looking at the thyroid tissue of four women with goiters an enlargement of the thyroid he found an excessive numbers lymphoid cells in the tissue samples He discovered that the thyroid was invaded by Tlymphocytes which hampered the gland s ability to properly function Hakaru didn t receive full credit for his discovery in Japan because he had chosen to publish his research in German and nobody in Japan could understand it American doctors believed He was the first to accurately describe Hashimoto s disease and the doctors commonly designated the disease by his name Endocrinology Part of the endocrine system composed of glands that produce endocrine secretions that help to control bodily metabolic activity the thyroid s most important function is to use iodine in the production of two vital hormones thyroxine T4 and



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