Scientific Methods andScientific Methods andProfessional EthicsProfessional EthicsPhysiology 411Physiology 411Course SyllabusCourse SyllabusFall 2010Fall 2010Gittings 201Gittings 201Monday-Wednesday-FridayMonday-Wednesday-Friday11-11:50 a.m.11-11:50 a.m.Gene Settle, Ph.D.Gene Settle, Ph.D.Office Hours:Office Hours: By Appointment By AppointmentOffice: Office: AHSC Room 4204AHSC Room 4204E-Mail: E-Mail: [email protected]@email.arizona.eduPhone: Phone: (520) 626-4252(520) 626-4252Syllabus, p. 2Syllabus, p. 2Scientific Methods and Professional EthicsScientific Methods and Professional EthicsPSIO 411PSIO 411Fall ‘10Fall ‘10COURSE OBJECTIVESCOURSE OBJECTIVES1. To introduce physiology students to the historical development of scientific scholarship; to foster an understanding of the philosophy of science; and to present selected current controversies withinthe scientific and medical communities.2. To develop a fundamental knowledge of the varied approaches to scientific methods and the application of these approaches to the biomedical sciences.3. To provide students with a basic background knowledge of experimental design and the elementary statistical procedures commonly used in physiological research.4. To familiarize students with the important procedural, practical, and ethical issues pertaining to biological research at a modern research university.5. To assess current public understanding of science.6. To afford students practical personal experience in selected areas of professional analysis and communication including (but not limited to) uses of the various forms of scientific literature; study, evaluation, and interpretation of selected scientific publications; basic scientific presentationskills; and preparation of personal statements, resumes, cover letters and other pre-professional materials. REQUIRED COURSE MATERIALSREQUIRED COURSE MATERIALS1. The following brief textbooks are required:(1) Gordon, John C. 2007. Planning Research. Yale University Press.(2) Glaser, Anthony N. 2005. High-Yield Biostatistics. Lippincott Williams & Wilkins.(3) Levine, Carol. 2010. Taking Sides: Clashing Views on Bioethical Issues, 13th Edition. McGraw-Hill.2. Course Readings held on ERes in the AHS Library. 3. Selected articles drawn from general media sources (periodicals, newspapers, etc.). PREREQUISITESPREREQUISITES2Completion of PSIO 201-202 with grades of “C” or better in both courses. Concurrent registration in PSIO 303A/304 (or completion of another upper division Physiology course) is highly recommended but is not required.Syllabus, p. 3Syllabus, p. 3EVALUATION PROCEDURESEVALUATION PROCEDURES(1) Midsemester Examinations (2). Each regular in-class examination will be 50 minutes in length and will be worth 150 points. (2) Final Examination. The final examination will consist of two parts: (1) Take-Home Portion; and(2) In-Class Portion. Questions will be assigned prior to the end of the semester. The written take-home questions will be due on December 13th at the beginning of the final examination; the in-class questions will be answered during the two hour period allotted for the formal final examination on December 13th, 2010. The final examination will be worth a total of 200 points.(3) Practicum Exercises (3). Each practicum will be worth 100 points and will cover selected topics in analysis, writing, and preparation of pre-professional materials. (4) Formal Classroom Discussions (10). Preparation for, and active participation in, the formal discussions will be worth a maximum of 200 points. Designated discussion leaders will be placedon stand-by status prior to each formal in-class discussion. The total points possible for PSIO 411 will be 1000. Final course letter grades will be determinedaccording to the following scale:90-100% (900-999 points) = “A”80-89.99% (800-899 points) = “B”70-79.99% (700-799 points) = “C”60-69.99% (600-699 points) = “D”59.99% and ↓ (599 and ↓) = “E”Percentage Grades will not be rounded upward in determining Course Letter Grades.No work for extra credit will be accepted to change any examination grade or the final course letter grade. Review of Exams 1 and 2 must be completed within ten days of grade posting.ACADEMIC INTEGRITYACADEMIC INTEGRITYThe University of Arizona Code of Academic Integrity will be enforced. The Code is accessible athttp://dos.web.arizona.edu/uapolicies/scc5308f.htmlASSESSMENT QUESTIONAIREASSESSMENT QUESTIONAIREA short assessment questionnaire will be given on the first day of class (August 23rd, 2010). Data obtained from the questionnaire will help determine the class structure for the remainder of the semester. A detailed lecture and examination schedule will be developed and made available by Wednesday, August 25th, 2010. 3Syllabus, p. 4Syllabus, p. 4Physiology 411Physiology 411Course Readings Spring ‘10Course Readings Spring ‘10(Posted on AHSL ERes)1. Woodward, James and David Goodstein (1996)“Conduct, Misconduct and the Structure of Science”American Scientist 84:479-4902. Wolpe, Paul Root (2006)“Reasons Scientists Avoid Thinking about Ethics”Cell 125:1023-10253. Shermer, Michael (2009)“I Want to Believe”Scientific American (July):33-354. Clement, Pierre and Marie-Pierre Quessada (2009)“Creationist Beliefs in Europe”Science 324:16445. Platt, J. R. (1964)“Strong Inference”Science 146:347-353 6. Couzin, Jennifer (2008)“Survey Finds Citations Growing Narrower as Journals Move Online”Science 321:3297. Evans, James A. (2008)“Electronic Publication and the Narrowing of Science and Scholarship”Science 321:395-3998. Alberts, Bruce, Brooks Hanson and Katrina L. Kelner (2008)“Reviewing Peer Review”Science 321:159. Raff, Martin, Alexander Johnson and Peter Walter (2008)“Painful Publishing”Science 321:3610. Marshall, Eliot (1998)“Medline Searches Turn Up Cases of Suspected Plagiarism”Science 279:473-47411. Long, Sharon and Robert Alpern (2009)“Science for Future Physicians”Science 324:124112. Oxley, Douglas R. et al. (2008)“Political Attitudes Vary with Physiological Traits”4Science 321:1667-1670Syllabus, p. 5Syllabus, p. 513. Friedman, Seth D. (2008)“Taking Responsibility for Scientific Discourse”Science 321:1039-104014. Denrell, Jerker (2008)“Indirect Social Influence”Science 321:47-4815. Pollard, Thomas D. (2002)“The Future of Biomedical Research”JAMA 287:1725-172716. Johnson, Joshua et al.