Computer assisted electroretinogram data acquisition and analysis Nick Balge, Andrew Dias, Whitney Johnson, Dan Jonovic Advisor: Professor Mitch Tyler Client: Dr. Bikash Pattnaik 12/11/200810/21/2008 2 of 28 Contents Table of Figures ............................................................................................................................................. 3 1. Abstract ................................................................................................................................................. 4 2. Background ........................................................................................................................................... 4 3. Applications/Motivation: ...................................................................................................................... 6 4. Problem Statement: .............................................................................................................................. 6 5. Lab layout: ............................................................................................................................................. 7 6. Design constraints: ................................................................................................................................ 7 7. The current interface ............................................................................................................................ 9 8. Design 1: Tweak Existing Interface ..................................................................................................... 10 A. Functionality ................................................................................................................................... 11 B. GUI Modification ............................................................................................................................. 11 9. Design 2: Complete GUI Overhaul ...................................................................................................... 13 A. GUI Plans ......................................................................................................................................... 14 B. GUI Design ....................................................................................................................................... 14 10. Design 3: Start over from scratch ................................................................................................... 16 A. Existing Solutions ............................................................................................................................ 16 B. Programming Languages ................................................................................................................. 16 C. Pros and Cons .................................................................................................................................. 18 D. The Design ....................................................................................................................................... 17 11. Design Matrix .................................................................................................................................. 18 A. Definition of Criteria ....................................................................................................................... 18 12. Results ............................................................................................................................................. 19 13. Testing ............................................................................................................................................. 22 14. Difficulties Encountered and Actions Taken ................................................................................... 23 15. Future Work .................................................................................................................................... 24 16. Conclusion ....................................................................................................................................... 25 17. References ...................................................................................................................................... 26 18. Appendix A: Product Design Specifications .................................................................................... 2710/21/2008 3 of 28 Table of Figures Figure 1: Example of ERG wave. ................................................................................................................... 4 Figure 2: Measuring the amplitudes and times of waves ............................................................................. 5 Figure 3: Organization of our client’s lab.. .................................................................................................... 7 Figure 4: A solution valve opener allows controlled flow of a chemical (Audie Technology, 2008). .......... 7 Figure 5: GUI for the original interface ......................................................................................................... 9 Figure 6: The existing backend ................................................................................................................... 11 Figure 7: Possible GUI Overhaul ................................................................................................................. 13 Figure 8: The Design Matrix ........................................................................................................................ 19 Figure 9: Sample output file ....................................................................................................................... 20 Figure 10: Final GUI ..................................................................................................................................... 2110/21/2008 4 of 28 1. Abstract The electroretinogram (ERG) records voltage responses of the retina to light stimuli. This project’s goal was to design an interface in LabVIEW that would monitor, control, and record values from the ERG corresponding to liquid delivery, light intensity, flash duration, flash frequency, and voltage responses. We integrated all of these controls while updating the graphical user interface (GUI) so that it was easy to navigate in a dark room under a red filter. Up to eight different solutions can be
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