Chemistry 143 Laboratory Fall 2008 Instructor Matthias Brewer Room A335 matthias brewer uvm edu 6 1042 T A Jodi Wyman Rm A328 Office hours 11 00am 12 00pm W F jodi wyman uvm edu Text Ault Techniques and Experiments for Organic Chemistry 6th Ed University Science Books 1998 Grading Quizzes 15 Technique 5 Lab report write ups 80 There are no make up lab sessions If you miss a lab for a valid i e medical or other true emergency reason you must provide your TA with a documented excuse for the absence The laboratory grade will be based on your general ability to carry out the experiments the accuracy with which you record and interpret your results and your performance on laboratory quizzes An example lab report will be handed out separately Note that messy or illegible lab reports will not be accepted Items that are not legible will be marked as incorrect and will not be considered for re grading Be careful with the carbon copy function of your lab notebooks Quizzes Quizzes will be given prior to the start of laboratory work They will cover material seen in previous lab sessions or material you should have learned as part of the prelab write up Chem 143 lecture material may also be included on these quizzes Technique This grade will be based on several factors including but not limited to the quality of the chemical samples you hand in your ability to conduct the experiment your safety practices and your housekeeping i e the cleanliness of your work area when you leave Lab report write ups The majority of your grade will be based on your lab write ups These will be due one week from the completion of the lab work These reports must be handed in at the beginning of the next lab meeting If you do not arrive to lab with a completed report ready to be handed in at the beginning of the next lab meeting your report will be considered late and will loose 2 points An additional 2 points will be docked each day the report is late Note that each lab report is only worth 20 points total The lab report should contain the following sections Prelab The T A will verify that a prelab has been satisfactorily completed before any lab work will begin If the prelab is not satisfactorily completed it will be assigned a grade of zero for its portion of the overall grade for this lab and the student will not begin lab work until the prelab is complete to the T A s satisfaction At a minimum the prelab must include the date a statement about the purpose of the lab a schematic drawing of the reaction to be done or a drawing of the important chemical structures to be purified a table showing the molecular weight density for liquids number of moles number of grams and number of mL to be used for each substance used in the lab a list of potential hazards and precautions to be taken a brief experimental procedure written in your own words that you will follow Note If you do not have a copy of the Aldrich Catalogue i e Aldrich Handbook request one at http www sigmaaldrich com Brands Aldrich html This is an invaluable free resource Chem 143 Laboratory Brewer M Observations and notes This section must include a detailed description of what you actually did and what you observed This should be in sufficient detail that anyone reading your notebook could repeat the process exactly as you did it Examples of standard notes and observations include the time something was added how long it took to add it how long materials were allowed to react gas evolution color change precipitate formation reproduction of TLC results including rf calculations tare weights weights or volumes of materials used etc Post lab write up This section is where a significant portion of the grade lies It should be a detailed discussion of the experiment including a discussion of the observations that you made the results that you obtained and an in depth description of the techniques you used This discussion should show that you not only understand exactly what you did but also should include a broader interpretation of what you learned through the experiment i e why the technique you learned is important and or an interpretation of your experimental results Post lab questions should also be answered in this section Academic Conduct Cheating will be considered grounds for failing the course All graded assignments must be your own work Cases of cheating or plagiarism will lead to further disciplinary action which may include dismissal from the University according to the rules set forth in The University of Vermont s Code of Academic Integrity General Considerations Read the assigned reading and write up your prelab before coming to class The experiments designated within each chapter describe the procedures that you will actually carry out in the laboratory For several of the labs a supplemental handout will be given that more fully describes the procedure to be done this is designated by H under Exp in the following table Date Handout or Exp Topic Reading Sept 9th 11th Introduction Safety Check in 1 41 Sept 16 18 Handout Melting point and solventless aldol condensation Lab Notebook and MP 44 45 150 158 Sept 23 25 Handout Solvent Recycling Simple distillation 62 78 138 149 Sept 30 Oct 2 Handout Fractional distillation GLC 70 72 122 128 Oct 7 9 Handout Thin layer chromatography 116 119 Oct 14 16 E 5 pg 337 340 Caffeine from Vivarin recrystallization 48 59 317 318 337 340 Oct 21 23 E9 Eugenol from clove oil extraction 92 106 346 Oct 28 30 Handout Liquid CO2 Extraction of Limonene Chem 143 Laboratory Brewer M Nov 4 6 Handout Synthesis of 5 10 15 20tetraphenylporphyrin and Column Chromatography Nov 11 13 E25 pg 402 403 Preparation of an n alkylbromide 402 403 Nov 18 20 E28 pg 407 409 Nucleophilic competition 407 409 Dec 2 4 E18 pg 381 384 Dehydration of methyl cyclohexanol 381 384 109 116 Laboratory Experiment Abstracts Introduction Safety Check in Be sure to check your equipment carefully Any broken or missing items which are cracked chipped or otherwise in less than perfect shape should be replaced by the stockroom You will be required to replace any missing or defective items at your expense at the end of the semester so make sure you start with a well stocked drawer of unbroken equipment Make sure your glassware is clean and dry before you begin your first experiment next week Melting point and Solventless aldol The purpose of this lab is to explore the technique of melting point determination and the effect of impurities on melting point You