Cardiovascular System 1

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Cardiovascular System 1

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University of Southern California
Bisc 307l - General Physiology
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BISC 307L 1st Edition Lecture 23 Current Lecture  Anatomy of Cardiovascular system o o Don’t need to know a lot of anatomy 3 essential things you need to know (diagram on right) o The only blood vessels across which exchange of material occurs are the capillaries o Two circulatory systems: pulmonary and systemic o The heart is two pumps in one o Right side pumps blood to lungs and left side pumps to body o Output of one is input of other o In some cases capillaries don’t lead into venules into veins (1. hypothalamic hypophyseal portal vein)  2. Second example is the blood supply to the liver- can receive blood through the hepatic portal vein (capillaries drain into veins)  positions the liver to handle the flood of nutrients that come out of the intestine during the absorptive state  3. Third portal system has the structure of the portal system is in the kidney – the glomeruler capillaries- the venules do not go to a vein into the heart but rather into another set of capillaries o Why do we need two hearts?  Fish only have one heart- won't ever amount to much  Next slide  Pressure, Flow, and Resistance o Advantage of two hearts  Relationship between pressure flow and resistance  What drives the flow  Fluids flow down pressure gradients (either liquids or gases) so in order to get blood to circulate there must be pressure gradients (hydraulic pressure) mmHg. High pressurelow pressure  Flow rate (Q) is proportional to the pressure gradient  Pressure is pushing flow through a resistance and so the rate is inversely proportional to resistance  Determinants of Vessel Resistance

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