CChheemm 44334433 BBiioocchheemmiissttrryy II Course Information Handout for Fall 2013 Lecturer: Dr. Eamonn F. Healy Office: JBWN 215 SEU Box: 805 e-mail : [email protected] Phone: 448-8467 http://www.cs.stedwards.edu/chem Office hours: Tue 2 -3.30 pm Thurs 2-3.30 pm Fri 11-1 pm (Other times by appointment) Prerequisite: Organic Chemistry I CHEM 2323 Schedule: Mon, Wed & Fri 10-10.50 JBWN 202 Reviews @ 4.45 pm in JBWN 102 (Monday Sept 16th & 23rd , Oct. 14th & 21st , Nov 18th) Text: Biochemistry by Mathews and van Holde, 3rd edition Deadlines: Wednesday, Sept. 11th for unrecorded drop or withdrawal. Tuesday, Nov.5th for withdrawal with grade W. Lucian Symposium, Friday, Oct. 18th Incompletes will be awarded only in emergency circumstances. Exams: Exam #1 Wednesday, Sept. 25th 20% Exam #2 Friday, Oct. 25th 20% Project Due on Mon Nov 18th 20% Quiz Wednesday, Nov. 20th 10% Presentations begin on Friday, Nov. 22nd Final Tuesday, Dec. 10th ( @ 11.15 am)30% Make-up exams may be given when circumstances warrant. All Exams are open-book and open-note (all notes must be on index cards) Homework will be for extra credit Grades: A : 90 - 100 % B : 80 - 89 % C : 70 - 79 % D : 60 - 69 % F : 0 - 59 % Academic The normal penalty for a breach of academic honesty is a grade of F for all Honesty those involved. Dishonesty is broadly defined as the representation of the work of others as ones own. Course To develop the students ability to understand and analyze the phenomena Objective asociated with biological processes from a molecular perspective. Syllabus Attached.CChheemm 44334433 BBiioocchheemmiissttrryy II Course Outline I Overview of Biochemistry (chpt. 1) II Essential Chemical Principles (chpt. 2-3) non-bonded interactions pp 27-32 aqueous solutions pp 33-38 acids, bases and buffers pp 40-47 thermodynamics pp 58-66 free energy & equilibrium pp 67-73 energy sources pp 73-78 III Macromolecular Strcuture : basic components of living matter (a) Nucleic Acids (chpt. 4) introduction pp 85-91 pp 124-125 primary structure pp 91-92 secondary structure pp 92-100 tertiary structure pp 100-103 pp 108-113 factors influencing stability pp 114-117 genetic expression pp 104-108 pp142-145 topic Drug-Resistant Bacteria (b) Proteins (chpt. 5-7) primary structure pp 127-142 secondary structure pp 161-176 tertiary structure pp 177-181 quaternary structure pp 195-198 protein folding pp 181-194 regulation pp 1032-1058 Hemoglobin pp 213-230 immunoglobulins pp 241-248 pp 954-957 topic Prions (c) Carbohydrates (chpt. 9) monosaccharides pp 279-290 derivatives pp 290-293 oligosaccharides pp 294-302 glycoproteins & glycolipids pp 303-311 pp 580-590 topic Blood group Type (d) Lipids (chpt. 10) structure of lipids pp 315-325 IV Enzymes : control of biochemical reactions (a) Introduction (chpt. 11) introduction pp 360-368 topic Gout (b) Catalysis mechanism of catalysis pp368-375 kinetics pp 375-383 topic Myocardial Infarction (d) Regulation inhibition pp 383-388 V Metabolism : Integration & Control (chpt. 23) structure and metabolism pp 830-834 Hormonal regulation pp 834-840 hormonal mechanism pp