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UCLA LIFESCI 4 - lifesci4_syl05s

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LS4-2 Spring, 2005.Christensen Merriam Lecture MWFDay Date TopicM 4/4 Mendel's Laws of InheritanceW 4/6 Probability and the Dihybrid CrossF 4/8 Pedigree AnalysisM 4/11 Mitosis, meiosis and chromosomesW 4/13 Sex-linked InheritanceF 4/15 Gene Linkage and RecombinationM 4/18 EXAM 1 (Through sex linkage) 5:00- 6:50 pm W 4/20 Linkage and gene mappingF 4/22 Mitchondrial Eve and Jefferson's YM 4/25 Population Genetics - Hardy Weinberg EqualibriumW 4/27 Population Genetics - InbreedingF 4/29 Bacterial genetics-Conjugation and Mapping IM 5/2 Bacterial genetics-Conjugation and Mapping IIW 5/4 Bacterial genetics-TransductionF 5/6 rII Phage and Gene StructureM 5/9 EXAM 2 (Through bacterial conjugation) 5:00- 6:50 pmW 5/11 Biochemical Pathways and Protein CodingF 5/13 Gene Interaction IM 5/16 Gene Interaction IIW 5/18 MutationF 5/20 Evolution of GenomesM 5/23 EXAM 3 (Through mutation) 5:00- 6:50 pmW 5/25 Molecular markersF 5/27 Genomics and the Human GenomeM 5/30 HOLIDAY- No LectureW 6/1 Genetic ScreensF 6/3 Sex Determination - DrosophilaM 6/6 Model organisms- ArabidopsisW 6/8 Genetics, Recombinant DNA and SocietyF 6/10 Final review/ evaluationsContact: Sioux Christensen, Office hours Friday 2-4, 328 Botany, ext 40018, [email protected] John Merriam, office hours, Tues 9-11 am, tenative, 4309 LSB 52256Required Course materials. Textbook is Introduction to Genetic Analysis: Griffiths, Edition 8. Availableat the ASUCLA Bookstore. Comes packaged with problem solutions manual and a CD, "Interactive Genetics"and the accompanying workbook. Copies of the CD are also on reserve in Powell Library and are installedin the Life Sciences computing center, 2127 Life Sciences Building.Grading. 3 midterms - 100 points each - lowest midterm score will be dropped (200 points). Cumulative final(250 points). 6 quizes -10 points each - lowest quiz score will be dropped (50 points). Total 500 points. Nomakeup quizes or exams will be given. Quizes will be given during discussion section. Each quiz will consist ofone problem taken directly from the problem set assigned the prior week. Quizes must be taken in thediscussion section in which you are enrolled.Workshops. Collaborative learning workshops will be offered every Tuesday and Thursday from 4-6. Thesework shops are optional and will provide you with an opportunity to work on the assigned problem sets as agroup. TA's will be available to provide insight into the problem solving process.Discussion section. TAs will answer questions about lecture material and problem solving. On first weekand exam weeks, discussion section will be held in the computer labs in Young Hall South.Office hours. Each of the five TAs will hold a weekly office hour. You can go any TA for office hours,irrespective of which TA leads your discussion section. Office hours and locations will be posted on the web site.Additional hours will be added during the weeks preceding the tests.Regrade policy. Regrades will only be considered for exams written in permanent blue or black ink, and are notencouraged unless there are obvious addition errors. All regrading requests must be submitted in writing to theLS core office.Course Web site. The main course web site is http://www.lsic.ucla.edu/classes. Course information includingthe syllabus, class announcements, office hours, problem sets and answer keys will be posted on the site. Inaddition color copies of the power point presentations for each lecture will be posted in pdf format.Administrative issues. For enrollment, illness absences or any other questions that do not directly pertain tothe material covered in the course, contact Mark Gray [email protected] 2305 Life Sciences, 310 825-6614.Reading and Practice ProblemsLecture Reading Chapter Problems Interactive Genetics CDMendel's Laws Chapt 2- pp 28-36 Chapt 2- 3, 9 Mendelian Analysis prob 1 & 2Fly Labprob 1-4Prob and Dihybrid Chapt 2- pp 36-40 Chapt. 2- 5, 10, 22, 23, 42, 48 Mendelian Analysis prob 3, 4, 5, 6 Pedigree and Prob prob 2 & 3 Fly Labprob 5 & 6Pedigree Analysis Chapt 2- pp 42-48 Chapt 2- 7, 15, 16, 17, 19, 21 Pedigree and Prob prob 1, 4, 5, 6Mitosis Meiosis Chapt 3- pp 75-80 Chapt 3- 18, 25, 26, 27, 40 Chromosomal Inheritance pp 90-96 allSex Linkage Chapt 2- pp 48-55 Chapt 2- 20, 25, 27, 30, 33, 54 X-linked Inheritance allLinkage & Recomb Chapt 4- pp 116-124 Chapt 4- 2, 3, 7, 8, 9, 15, 17, 41 Linkage pp 131-133 prob 1-4 Chapt 2- pp 40-42Linkage & Mapping Chapt 4- pp 124-127 Chapt 4- 11, 20, 33, 36, 37, 40 Linkage prob 5 & 6Mito Eve & Jeffs Y Chapt 21- pp 693-696 ------ ------Pop. Genetics - HW Chapt 19- pp 612-624 Chapt 19- 2, 3, 10, 12, 15 Population Genetics allPop. Gen. - Inbreed Chapt 19- pp 625-626 Chapt 19- 16 ------Lecture Reading Chapter Problems Interactive Genetics CDBact Conjugation Chapt 5- pp 152-165 Chapt 5- 6, 8, 13, 22, 23, 25, 26 Bacterial Genetics- I & II 27 Conjugation allBact Transduction Chapt 5- pp 170-175 Chapt. 5- 17, 20, 21, 28, 31 Bacterial Genetics- Transduction allrII Phage Chapt 5- pp 166-170 Chapt 6- 19, 49, 66 ------Chapt 6- pp 199-203 Chapt15- 26Biochemical Path Chapt 6- pp 186-192 Chapt 6- 2, 4, 5, 6, 21, 22, 50 Biochemical Genetics allGene Interaction Chapt 6- pp 192-199 Chapt 6- 9, 10, 11, 12, 13, 18, Genotype/Phenotype I & II pp 203-209 24, 26, 29, 32, 45, 57, 64 allMutation Chapt 14- pp 452-468 ------ ------ Evol of Genomes TBA TBA -------Molecular Markers Chapt 12- pp 398-402 Chapt 12- 35, 36 Molecular Markers allGenomics Chapt 12- pp 390-398 Chapt 12- 6, 22, 26, 31, 34 Gene Cloning allGenetic Screens Chapt 16- pp 522-530 ------- -------Arabidopsis Chapt 18 - pp 603-605 -------


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