Animal Health 1Exam # 1 Study Guide Lectures: 1 - 4Lecture 1 (8/22/13)Introduction to disease1.Infectious vs non-infectious2.Contagious vs non-contagious3.Direct and indirect transmissionInfectious disease process:1.Enter host2.Multiply3.Evade host defenses4.Harm hostOther definitions:1.Epidemic2.Endemic3.Pandemic4.Commensalism5.Parasitism6.Mutualism7.Pathogenicity8.Virulence9.Infectious dose (ID50 and LD50)Pathogen types:1.Obligate vs opportunistic(potential)2.Frontal vs stealth assault3.Final, intermediate and reservoir hostHost defenses:1.Innate vs inducible 2.Defense mechanisms a. Physicalb. Cellularc. Immunologicald. Non-specific Physical defenses:1.Respiratory2.Gastro-intestinal3.Urogenital4.Mammary5.Transmission of pathogens6.Attachment and adherence7.Defenses against adherencea. pH, secretions, normal flora, flushing8.upper respiratory9.dermalLecture 2 (8/27/13) 1.primary and secondary lymph tissue. Know them and describe the afferent and efferent components2.know thymus positive and negative selection3.know different cells in cellular defense and their role and what they producea. monocytesb. dendrite cellsc. neutrophilsd. phagocytese. basophilsf. T and B cellg. What plasma cells are4.Know some defenses against the host (in terms of the pathogen)Lecture 3 (8/29/13)1. Know what cells have MHC1 and MHC2 and what they do2.Know the difference between CD4+ and CD8+3.Review AIDS4.Know the immune response sequence5.Definition of antibody, what the look like and know each part6.Know all the different kinds of antibodies in detailLecture 3 (9/3/13)1.Know the functions of cytokines and which cells produce cytokines2.Know non-specific immune responsea. Complement b. Lactoferrin3.Helminthesa. Specific defensesb. SIZE problemc. IgE responsed. Worm defensese. Immunosuppression and why its important4.Cancera. Know how it can happenb. Know definitionc. Generally non-viral5. Fevera. Good vs badb. Know the process of a fever including:i. Interleukin 1ii. Arachidonic acidiii. Prostaglandin Eiv. Hypothalamus6.Know the relative size of all the parts involved with the immune