Slide 1Slide 2Slide 3Slide 4Slide 5Slide 6Slide 7Slide 8Slide 9Slide 10Slide 11Slide 12Slide 13Slide 14Slide 15Slide 16Slide 17Slide 18Respiration During ExerciseTerms•Ventilation•Respiration•Pulmonary respiration•Cellular respirationVentilation•Respiratory Muscles•Inspiration•Diaphragm (rest and exercise)•External intercostal muscles (exercise)•Others (exercise)•Expiration•Internal intercostal muscles (exercise)•Abdominal muscles (exercise)FYIStructure of the Respiratory System•Conducting Zone•Respiratory Zone•AlveoliRespiration•PO2 inside the venous blood = 40 •PO2 inside the alveoli = 100 •Therefore, O2 flows from the high pressure (lungs) to the low pressure (blood)•PO2 inside the arterial blood = 100PO2 = 40PO2 = 100PO2 = 100RespirationPO2 = 100PCO2 = 407PO2 = 40Pulmonary RespirationCellular RespirationOxygen SaturationSea level = 97%SaturationSea level = 97%SaturationMount Everest = 48%SaturationMount Everest = 48%SaturationThe Pulmonary System & ExerciseControl of VentilationCO2CO2Ventilation & Steady State ExerciseVentilation & Graded ExerciseNote the non-linear Note the non-linear increaseincreasein ventilationin ventilationVentilation ThresholdCO2 from Krebs cycle stimulates ventilationCO2 from Krebs cycle an d buffering lactic acid stimulate ventilation even fasterAerobicAerobic andAnaerobic13Ventilatory & Lactate ThresholdsExercise “Talk Test” 3 4 5 6 7 8 9 10 11 mphVentilation & Exercise•Does the pulmonary system limit exercise performance?•Untrained - fatigue of respiratory muscles•Trained - greater than 80% of max and longer than 10 min•Exercise-induced hypoxemiaTraining20-30% decreaseTraining•Do the lungs adapt to exercise training?•Do the respiratory muscles adapt to exercise training?Respiratory MusclesInspirationDiaphragm (rest and exercise)External intercostal muscles (exercise)Others (exercise)ExpirationInternal intercostal muscles (exercise)Abdominal muscles (exercise)Pulmonary Diseases•Exercise induced asthma•Chronic obstructive lung disease