Penn CAMB 632 - CAMB 632 SYLLABUS (2 pages)

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CAMB 632 SYLLABUS



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CAMB 632 SYLLABUS

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Pages:
2
School:
University of Pennsylvania
Course:
Camb 632 - Cell Control by Signal Transduction Pathways

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CAMB PHRM 632 Syllabus 2012 Spring Course Directors Xianxin Hua 412 BRB II III Jeffrey Field 626 CRB Margaret Chou 816E ARC Guest Faculty Warren Pear Peter Klein Michael May 611 BRB II III 364 CRB 200E VET 215 746 5565 215 898 1912 267 426 9228 huax mail med upenn edu jfield upenn edu mmc mail med upenn edu 215 573 7764 215 898 2179 215 573 0940 wpear mail med upenn edu pklein mail med upenn edu maym vet upenn edu When Fridays 11 00PM 1 00PM Where Room 901 BRB II III How do extracellular signals regulate cells and how do cells respond to these signals Answers to these questions are crucial for understanding the molecular cascades that control cell function tumorigenesis and ultimately developing targeted therapies This course Cell control by signal transduction pathways will examine how various signal transduction pathways influence cell functions such as gene transcription protein translation intracellular protein trafficking and cell proliferation The primary signal transduction pathways to be examined include those mediated by PI3 kinase Notch TGFbeta NF kB Wnt and Ras Objectives After taking this course participants will 1 Become familiar with the principle of cellular signal transduction pathways regulation of cellular behavior by the pathways and typical approaches to investigation of signaling pathways 2 Further develop and strengthen skills that are critical for success in scientific research These include critical analysis of the scientific literature generation of testable new hypotheses based on the literature and oral and written scientific presentations Presentation 1 In the first half of the seminar course in each class session each of two students will be assigned a paper related to a specific signaling pathway The students will have an opportunity to discuss with a guest faculty member the background scope and critical points in the paper prior to presentation In addition the faculty member will provide one or two reviews that are closely related to



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