BIOL 1344 Lecture 17 Outline of Last Lecture I. Anatomy of Lung – Mechanics of BreathingA. Quiet BreathingB. Forced BreathingC. Lung Pressure D. Air FlowE. Lung Diseases Outline of Current Lecture I. Gas Transport in the BodyA. Laws Concerning Gas TransportB. Pressures of Air at Sea LevelII. Solubility of GasCurrent LectureUptake and Transport of Gases- Boyles Law- Dalton’s Law – partial pressures of gases- Henry’s Law – solubility - Haldane’s Law – effect of carbon dioxide on oxygen transport- Bohr’s Law – effect of acidity on oxygen uptakeAir flows based on the pressure gradient, from high pressure to low pressure areas. Air at sea level is 760 mmHg. Breakdown of this air outside the body is Nitrogen (79%), Oxygen (21%), water vapors (.46%), and carbon dioxide (.04%). In alveoli pressures change: PO2 (partial pressure of oxygen) (13.7%, 104 mmHg) this is also 98% saturated with hemoglobin, carbon dioxide (5.2%, 40 mmHg), water vapors (46 mmHg). In high altitudes these pressures change and PO2 drops which is why there is breathing difficulty at 8,000-12,000 feet. At 60,000 feet pressures drop so low that bodily fluids start boiling at 37 degrees Celsius which is why a pressure suit is needed.Henry’s Law concerns solubility. Carbon dioxide is readily soluble while oxygen is 24 times less soluble though nitrogen is the least soluble. In hemoglobin, 1.33 ml of oxygen/gram of Hb. Therefore, 15 grams of Hb = 20 ml oxygen/100 ml of blood which is 100% saturation. Tissues These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.extract 5 ml of oxygen per 100 ml of blood and we need 250 ml of oxygen per minute so (100 X 250 / 5 = 5,000 ml/min) which is the cardiac
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