BIO-L104 1nd Edition Lecture 14 Outline of Last Lecture I. Lecture with Kathleen BakerOutline of Current Lecture II. Dr. Seth Judd talks about Panic DisordersCurrent LecturePanic disorder- Recurrent, spontaneous, primary, panic attacks- Aggressively help-seeking- Patients often lead you to the diagnosis in the open-ended question portion of the interview- 50% of patients have chronic illness- Complicated by comorbidity- Common disorder 2-3% of adults and .9% of adolescents - Cost of anxiety disorders in the U.S estimated at 42.3 Billion (1990 dollars)Biological Basis of Anxiety Disorders- Familial pattern- Characteristic clinical course- Typical pharmacological response- Neuroimaging findings- Animal experimentationNeurochemistry of Panic disorders- Serotonin: innervates regions of the brain that regulate fear and worry - Norepinephrine: in excess it reduces the efficiency of information processing in the PFC leading to feelings of anxiety and worry. - Phobic individuals tend to have a higher baseline NE level and greater release in response to anxiety inducing triggersWhy would we then use a drug that increases norepinephrine to treat anxiety?These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.GABA vs. GlutamatePTSD- Antecedent history of trauma- Re-experiencing symptoms- SSRI typically given, for combat vets we typically use
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