Lecture 22Outline of Last Lecture 1. Levels of Chemical Decontamination2. Detergents & Soaps3. Treatment & Prevention of DiseaseOutline of Current Lecture 1. Antimicrobial Compounds2. ResistanceCurrent LectureAntimicrobial compounds- Resistance- Short generation time - Ways of getting new DNAInherent Resistant- Something about organism already exists that makes resistant to antibioticsAcquired Resistant- Once susceptible, but now can fight antibiotic. Because of…- Gene mutation BSC 160 1nd Edition- Mutation of transport proteins- Acquisition of gene for efflux- Acquisition of gene for drug modificationUnnecessary use of antibiotics- Over the counter sales - Discounting before doneAntimicrobial compounds- Strategies for reducing the speed of resistance expansion1. Limit the use2. Educate the public & medical community3. Verify completion4. Cycle the use of antibiotics5. New
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