BIOL 640 1st Edition Lecture 18Outline of Last Lecture I. T cell activation Outline of Current Lecture II.HIVIII. Adoptive transfersIV. Cell cooperationCurrent LectureImmunology: Lecture 19- Immunodeficiency : HIV:In patients with HIV CD4 count goes to zero. They die from other infections.When human has no gene for CD4 cells (natural knock out), virus in serum but can not enter CD4 cells and not propagate.Molecular targeting is not effective as virus mutates. But when CCR5 are absent, cells are fine.Adoptive transfers:Stromal cells are radiation resistant. All cells are chimeric. Placenta allows Ig G to pass through. Stem cellulite cells can pass from mother and lactation stem cellulite cells end up in tonsils.More humanized mouse where sets of genes are replaced with human cells in order to study impact of human diseases.Cell co-operation:Adherent cells- macrophagesThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.Floater cells- lymphocytesMacrophages by phagocytosis of Ag can form Ag
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