DOC PREVIEW
UWL BIO 312 - Integumentary system

This preview shows page 1 out of 2 pages.

Save
View full document
View full document
Premium Document
Do you want full access? Go Premium and unlock all 2 pages.
Access to all documents
Download any document
Ad free experience
Premium Document
Do you want full access? Go Premium and unlock all 2 pages.
Access to all documents
Download any document
Ad free experience

Unformatted text preview:

Lecture 7 Lecture Outline:I Integumentary systema. Dermis histologyb. Subcutaneous layer (hypodermis)II Skin cancer a. Basal cell carcinomab. Squamous cell carcinomac. Malignant melanomaIII Burnsa. First, second, third degreeHistology of Skin:- Epidermis: keratinized stratified squamosal epithelium- Dermis: second layer of skin, composed of two layerso Papillary layer: consists of areolar connective tissue Lots of blood vessels Dermal papillae: increase surface area between epidermis and dermis to hold together bettero Reticular layer: makes up most of the dermis Composed of mainly collagen fibers with elastic fibers Dense irregular connective tissue (leather) Lines of cleavage: Most collagen and elastic fibers in any location of dermis arranged in parallel- Orientation depends on stress placed on skin during normal movement- A cut parallel to line of cleavage usually remains closed- A cut at right angle will be pulled open as cut elastic fibers recoilo Contains blood vessels, lymphatic ducts, sensory receptorso Contains hair follicles and accompanying sebaceous glands Arrector pili muscle: band of smooth muscle , responsible for goose bumps- Subcutaneous layer (hypodermis): contains larger blood vessels, adipose tissueo Good injection site because no vital organsCancer: a particular cell type undergoes uncontrolled cell multiplication and growth- Can be described aso Malignant: has ability to metastasize/move to other parts of the bodyo Benign: does not spread to distant locationso Primary: cancer originated in the spot of the body that it currently iso Secondary: cancer that originated in another location of the body and metastasized to its current location- Skin Cancer: induced by ultraviolet rays of the sun, UVA and UVB rays are both harmfulo Most prevalent of all cancers (1 out of 5 Americans)o Incidence has increased by 800% in last 50 yearso Everyone is at risk but fair skinned individuals most at risk (blondes & redheads)o 3 main types named for cell sin epidermis that they arise fromBio 312 Basal cell carcinoma: most common type but the least malignant- Arises from cells in stratum basale, eventually invades dermis- Lesion first appears as small shiny bump, later develops central ulcer- Surgical removal (99% cure) Squamous cell carcinoma: arises from keratinocytes in stratum spinosum- Appears as raised, reddened, scaly bumps- Later forms a concave ulcer with raised edges- Cure rate high if detected and treated early, otherwise can metastasize to lymph nodes Malignant melanoma: arises from melanocytes- Most deadly because it metastasizes quickly and resistant to chemotherapy- Early detection is the key to survival,- ABCDE rule: asymmetry, Border irregularity, Color, Diameter, ElevatedBurns: a leading cause of accidental death- Urgent considerations in treatment are fluid replacement (can lose up to 75% of plasma within a few house), infectioncontrol, administration of excess calories to replace lost proteins and precursors for tissure repair- Classified by the depth of the burn:o First degree burns: involves epidermis only, heal in a few days, rarely leaves scars (sun burn)o Second degree burns: involves part of dermis, may take weeks to months to heal, probably leave scarso Third degree burns: all layers of skin and often deeper tissues, often require skin grafts, area is often left painless because of the destroyed sensory


View Full Document

UWL BIO 312 - Integumentary system

Download Integumentary system
Our administrator received your request to download this document. We will send you the file to your email shortly.
Loading Unlocking...
Login

Join to view Integumentary system and access 3M+ class-specific study document.

or
We will never post anything without your permission.
Don't have an account?
Sign Up

Join to view Integumentary system 2 2 and access 3M+ class-specific study document.

or

By creating an account you agree to our Privacy Policy and Terms Of Use

Already a member?