VCU BIOL 310 - Chromosomes and Mitosis (7 pages)

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Chromosomes and Mitosis

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Chromosomes and Mitosis


Notes on chromosomes and mitosis in a geneticists perspective.

Lecture number:
Lecture Note
Virginia Commonwealth University
Biol 310 - Genetics

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BIOL 310 1st Edition Lecture 6 Outline of Previous Lecture Mendelism I Chi squares II What are genes and where are they located a Discoveries post Mendel Outline of Current Lecture I II Chromosome Types Translocation Mitosis and Meiosis are part of the cell cycle a Chromosome structure I Chromosome Types and Translocation Morgan connected a specific phenotype to a specific chromosome Specifically the X chromosome with the white fly gene o His data was consistent with the law of segregation Carothers 1913 Used chromosome translocations in grasshopper gametes to show that non homologous chromosomes o Discovered translocation genes exchange onto different chromosomes during replication o 1 2 E1 E2 E3 E4 X 1 2 represents a translocation What Mendelian expectation hypothesis did this observation address and how These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute o Carothers hypothesis was just another phenotype observation she just needed a microscope to see them Her hypothesis and findings supported the independent assortment model Blakeslee 1922 Showed that Datura plants with an extra chromosome had How did these observations expand ideas about unit factors Showed that multiple genes were on a single chromosomes there are 12 homologous pairs on a chromosomes Trisomics for different chromosomes produce different phenotypes II MITOSIS AND MEIOSIS ARE A PART OF THE CELL CYCLE MITOSIS equally divides the chromosomes only in somatic cells Cytokinesis divides equally among daughter cells G1 cell contents DNA duplicate G0 stays in G1 for a long time neurons S DNA histones are synthesized G2 Mitosis or DIE MEIOSIS a Chromosome Structure Chromosome nomenclature G1 chromosome end of mitosis single strand Has one DNA duplex nomenclature sister chromatids during the S Phase X Has 2 DNA duplex Nomenclature X Centromeres cant be at the tippy top because telomeres must be there

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