SC BIOL 541 - Co-enzymes and Co factor (5 pages)

Previewing pages 1, 2 of 5 page document View the full content.
View Full Document

Co-enzymes and Co factor



Previewing pages 1, 2 of actual document.

View the full content.
View Full Document
View Full Document

Co-enzymes and Co factor

281 views


Lecture number:
10
Pages:
5
Type:
Lecture Note
School:
University Of South Carolina-Columbia
Course:
Biol 541 - Biochemistry

Unformatted text preview:

BIOL 541 1st Edition Lecture 10 Outline of Last Lecture I Allosterism Outline of Current Lecture II Co enzymes III Co factors IV General Mechanism Current Lecture Biochem Lecture 10 Co enzymes Cobalamin Vitamin B12 It is one of the lsrgest with center of Cobalt anf not Fe as in heme Side chains are adenine nucleotide with sugar residue as side chains It is not well absorbed from the gut but requires intrinsic factor such as protein secreted by the cells of the stomach Pernicious anemia develops if the system is affected Treatment is given by B12 injections administered by medical staff Reaction Catalysis Reduction reaction of nucleotide such as oxygenated nucleotide to deoxygenated nucleotide for synthesis of DNA Catalysis transfer reaction occurs where the x group is flipped to adjacent carbon by pulling off the H and free radical H is formed The X group hops into the space and H is added to the adjacent C X can also be OH group 1 Diol dehydratase OH H forms water which is removed as flipping causes both OH groups close together Thus the final product is from a diol to aldehyde These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute 2 Ethanolamine Ammonia lyase H switches with H2N and H2N and H form ammonia The end product is aldehyde 3 C C bonds are strong but can be switched Glutamat mutase can flip COOH to another C forming gamma acid Co factors In organic molecules example metal ions which help enzymes 1 Act as electrophilic groups They are very positively charged and pull electrons as extreme liking for electrons This creates a strain on the bonds created so they become susceptible to attack It can be used to coordinate electronegative groups for example a Zn in carboxy peptidase A b Mg phosphorylase where Mg regulates the ezyme that removes the phosphate group and adds Mg instead c Mn arginase in urea cycle 2 Valence change involved in oxidation reduction reaction



View Full Document

Access the best Study Guides, Lecture Notes and Practice Exams

Loading Unlocking...
Login

Join to view Co-enzymes and Co factor and access 3M+ class-specific study document.

or
We will never post anything without your permission.
Don't have an account?
Sign Up

Join to view Co-enzymes and Co factor and access 3M+ class-specific study document.

or

By creating an account you agree to our Privacy Policy and Terms Of Use

Already a member?