CALIFORNIA STATE POLYTECHNIC UNIVERSITY, POMONACHE499 TRANSPORT MODELING Spring 2008Prerequisites: MAT 216, a course in thermodynamics, and a course in fluid mechanics or heat transfer.Instructor: Thuan K. Nguyen Office Hours MTW 1:00-2:30 PM, Th 7:15-8:00 AMRoom: 17-2108 Phone: 869-2631TEXT: Basic Transport Phenomena in Biomedical Engineering by FournierREFERENCES:(1) Introduction to Bioengineering by Berger, Goldsmith, and Lewis(2) Transport Phenomena in Biological Systems by Truskey, Yuan, and Katz, Prentice Hall, 2004(3) Cellular Biophysics by Thomas Weiss by Bailey and Ollis(4) Transport Phenomena by Bird, Stewart, and LightfootGRADE:No late homework. No make-up quizzes or testsHomework (best 8 of 9 assignments) 15%Best 4 of 5 biweekly quizzes 45%, closed books and closed notesFinal 40Case Study (Optional) 5%A : 93-100%, A- : 90-93% , B+ : 87-90% , B : 83-87% , B- : 80-83% C+ : 77-80% , C : 73-77% , C- : 70-73% D+ : 67-70% , D : 60-67% , F : 0-60%April 4 Assignment #1 dueApril 11 Assignment #2 due. Quiz #1April 18 Assignment #3 due.April 25 Assignment #4 due. Quiz #2May 2 Assignment #5 due.May 9 Quiz #3May 16 Assignment #6 due.May 23 Assignment #7 due. Quiz #4May 30 Case Study and Assignment #8 due.June 6 Assignment #9 due. Quiz #5Final Exam: Wednesday June 11, 9:10 AM-11:10 AMStandard Format for Chemical & Materials Engineering ProblemsAn engineer's work should be neat, well organized, and easy to follow. You are expected tofollow this standard format for completing chemical & materials engineering problems. Pointsmay be deducted for work that does not adhere to this format.1. Use 8.5x11 paper for engineering problems.2. The problem statement is needed before the solution ; a drawing is usually required.3. No credit will be given for final answers that do not show work involved.4. Draw a box around your answers. Be sure to include units.5. The top of each page should contain the following information from left to right:Course & Section # | Assignment # | Your last name, 1st name | Page #/Total pages6. Staple all pages of an assignment together in the upper left corner.CALIFORNIA STATE POLYTECHNIC UNIVERSITY, POMONACHE499 TRANSPORT MODELING Spring 2004COURSE DESCRIPTIONSThis course provides an introduction to the modeling of mass- and momentum-transportprocesses in biomedical engineering. It discusses examples of transport processes relevant to thedevelopment of artificial organs, bioartificial organs, controlled drug delivery systems, andtissue engineering. This course stresses the fundamental principles underlying transportphenomena in various areas of biomedical engineering. Mathematical models are developedusing the “shell balance” or compartmental approaches. Some analytical and numerical methodswill be introduced to solve the transport equations.COURSE OUTLINEWEEK TOPICS READING ASSIGNMENTS 1 Physical Properties of The Body Fluids Chap. 1 The Thermodynamics of Osmosis Capillary Filtration Rate 2 Solute Transport in Biological Systems Chap. 2 The Irreversible Thermodynamics of Membrane Transport. 3 Transport of a Solute Between a Capillary Chap. 2 and the Surrounding Tissue Space Solute Transport in a Vascular Bed4 Hemodialysis.Design of an Artificial Kidney UtilizingUrea in Polymeric Beads. 5 The Physical and Flow Properties of Blood Chap. 3 Rheology. The Hagan-Poiseuille Equations6 Velocity Profile for Tube Flow of a Casson Fluid Rheology of Blood. Marginal Zone Theory Generalized Mechanical Energy Balance Equation 7 Oxygen Transport in Biological Systems Chap. 4 The Hill Equation. Tissue Oxygenation8 Oxygen Transport in a Bioartificial Organ and in the Krogh Tissue Cylinder. Approximate Solution 9 Pharmacokinetic Analysis Chap. 5 First-Order Drug Absorption and Elimination. Two-Compartment Models 10 Extracorporeal Devices Chap. 6 Blood Oxygenators. Oxygen and Carbon Dioxide