Pitt NUR 0012 - Tonicity (4 pages)

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Lecture number:
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University of Pittsburgh
Nur 0012 - Anatomy and Physiology I
Anatomy and Physiology I Documents

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Nur 0012 Lecture 7 Anatomy and Physiology 1 Lecture Jason Dechant Outline of Last Lecture I Plasma membrane fluid mosaic model A Integral proteins receptors enzymes channels CAMs B Peripheral proteins C Microvilli D Cilia II Membrane transport A Interstitial space extracellular space intracellular space B Passive transport diffusion facilitated diffusion osmosis tonicity C Active transport Outline of Current Lecture I Tonicity A Isotonic B Hypotonic C hypertonic solutions II Active transport A Primary active transport B Secondary active transport These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute C Bulk transport exocytosis endocytosis D Cell structures mitochondria ribosomes rough ER smooth ER E Mitosis interphase prophase metaphase anaphase telophase cytokinesis F DNA transcription translation RNA polymerase Current Lecture I II Tonicity most cells have same concentration inside and outside the cell A Isotonic intracellular fluid 9 saline and interstitial fluid 9 saline normal 1 No net change in cell size no negative impact on cells B Hypotonic less solutes outside cell water rushes into cell causing it to swell and can eventually lyse rbcs release hemoglobin when lyse 1 If cells swell in CNS it starts to push against skull can lead to death C Hypertonic more solute outside of cell water rushes out of cell causing it to shrivel crenate which can lead to dehydration 1 Can add proper concentrations with IV Active transport requires ATP moves solutes against concentration gradient A Sodium potassium pump Na K every cell membrane has some form of it nerve and muscle cells use them to do work 1 Carrier proteins specific for sodium entering the cell more potassium in the cell wants to get out but they can t because of their charge that s where the carrier proteins come in 2 An example of primary active transport using only one channel pumping ions against concentration

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