IUB BIOL-L 211 - Drosophila as a Model System (3 pages)

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Drosophila as a Model System



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Drosophila as a Model System

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Drosophila as a Model System Discoveries in Genetics Major Researchers


Lecture number:
3
Pages:
3
Type:
Lecture Note
School:
Indiana University, Bloomington
Course:
Biol-L 211 - Molecular Biology
Edition:
1
Documents in this Packet

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BIOL L 211 Lecture 3 Outline of Last Lecture I Pangenesis II Lamarckism III Blending Theory of Inheritance IV Arrival of Gregor Mendel Outline of Current Lecture I Drosophila Melanogaster A Model Organisms B Drosophila in Research C Important Researchers D Discovery of Sex Linked Traits II Crossing Over A Proximity Factor B Crossing Over III Additional Points A Incomplete Dominance B Co dominance Current Lecture Drosophila As a Model System I Drosophila Melanogaster common fruit fly A Drosophila Melanogaster is what is known as a model organism 1 A model organism is a non human widely studied organism with a genome that is easily sequenced and similar to humans 2 Common model organisms drosophila melanogaster yeast E Coli and arabidopsis thaliana These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute B Drosophila Melanogaster in research 1 Has only 4 chromosomes which facilitates gene manipulation 2 Life cycle of only 10 days speeds up research results obtained quickly 3 Flies are compared to the wild type which is the normal type C Important People in Research of the Drosophila Melanogaster 1 William Ernst Castle 1906 First to use flies 2 Thomas Hunt Morgan 1933 Nobel Prize for his research in the field of genetics specifically with individual chromosomes 3 Herman Muller 1946 IU Professor Demonstrated that x rays cause mutations which is good to know 4 Dr Kaufman 2014 Discovered 1 468 new genes in the drosophila melanogaster genome post the genome being sequenced D Discovery of Sex Linked traits via Drosophila Melanogaster 1 Examined progeny of mutant male with white eyes 2 Found that eye color was only transmitted with X chromosome 3 With only one X chromosome present in males the x linked gene could be expressed II Crossing Over A Proximity factor 1 Thomas Hunt Morgan mentioned earlier noted that some allele combos inherited more frequently than others 2 Andrew



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