Lecture 3Outline of Last LectureI. AnatomyII. LesionsIII. RecordingIV. MRIOutline of Current LectureI. StimulationII. BehaviorIII. Other ExperimentsIV. Intro to ElectricityV. Abbreviation KeyCurrent LectureA. Stimulationa. Current goes through electrode in order to stimulate the neuron for a responseb. OptogeneticsB. Behaviora. Morris water maze: rat finds platform by chancei. With multiple trials, is conditioned to find the platform very quicklyii. If there is hippocampus damage or removal, the mouse will take just as long on the 35th try as he did on the 1st b. 2 types of behavioral approaches i. Choose behavior because it’s what you want to learn about ii. Choose behavior because it’s a window for a particular brain system or processiii. EX: Morris water maze; could be either…1. Want to study memory2. Want to understand the hippocampusC. Other Experimentsa. Molecular/geneticsb. Computational neuroscience (simulations)D. Intro to Electricitya. CHARGE!!!b. Ohms Law: V=IRi. as neuroscientists, we must also account for capacitance which changes over timec. capacitor: thin barrier between two things will create a differencei. neurons are capacitors, which cause delayii. charge builds on one side and will attract the opposite charge to it NEU 330 1st Editiond.dVmdt=ℑC (if there’s a net change in current, the voltage will also change)E. Abbreviation key:a. Current: change in movement of chargeb. Volts: makes current goi. EMFii. What makes charge movec. Ion channels open -> increased conductanceq ChargeI CurrentV VoltageR Resistanceg Conductancec Capacitance NEU 330 1st