IUB BIOL-L 211 - New Life for Ancient DNA (2 pages)

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New Life for Ancient DNA



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New Life for Ancient DNA

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First Day of Class "New Life for Ancient DNA" Article


Lecture number:
1
Pages:
2
Type:
Lecture Note
School:
Indiana University, Bloomington
Course:
Biol-L 211 - Molecular Biology
Edition:
1
Documents in this Packet

Unformatted text preview:

BIOL L 211 1st Edition Lecture 1 Lecture Notes Note First day of lecture minimal material covered I Molecular Biology in the News A Article New Life for Ancient DNA Scientific American August 2012 1 Genetic study performed with a preserved mammoth 2 Purpose to evaluate the influence of mammoths genetic makeups on the ability of their hemoglobin to function despite cold temperatures a Hemoglobin a protein binds to oxygen in lungs and delivers it to tissues throughout the body b Hemoglobin does not readily release oxygen in cold temperatures c Resulting question How did mammoths adapt such that their hemoglobin was unimpaired by the cold temperatures 3 Procedure a Researchers sequenced the mammoth hemoglobin gene from preserved fragments b Next the sequenced gene was compared to the hemoglobin gene from a modern day elephant c The mammoth gene differed from the elephant by three nucleotides 4 Drawing a Conclusion was then a The new hemoglobin gene was introduced to E Coli which are excellent for rapidly producing copies of genes and the E Coli exposed to cold temperatures b The result confirmed that the E Coli was better adapted to the cold environment with the new gene sequence These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute c Researchers were able to conclude that the mammoth s hemoglobin gene sequence did specifically code for a mechanism to allow hemoglobin to function despite cold temperatures



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