IUB BIOL-L 211 - New Life for Ancient DNA (2 pages)
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First Day of Class "New Life for Ancient DNA" Article
- Lecture number:
- 1
- Pages:
- 2
- Type:
- Lecture Note
- School:
- Indiana University, Bloomington
- Course:
- Biol-L 211 - Molecular Biology
- Edition:
- 1
Unformatted text preview:
BIOL L 211 1st Edition Lecture 1 Lecture Notes Note First day of lecture minimal material covered I Molecular Biology in the News A Article New Life for Ancient DNA Scientific American August 2012 1 Genetic study performed with a preserved mammoth 2 Purpose to evaluate the influence of mammoths genetic makeups on the ability of their hemoglobin to function despite cold temperatures a Hemoglobin a protein binds to oxygen in lungs and delivers it to tissues throughout the body b Hemoglobin does not readily release oxygen in cold temperatures c Resulting question How did mammoths adapt such that their hemoglobin was unimpaired by the cold temperatures 3 Procedure a Researchers sequenced the mammoth hemoglobin gene from preserved fragments b Next the sequenced gene was compared to the hemoglobin gene from a modern day elephant c The mammoth gene differed from the elephant by three nucleotides 4 Drawing a Conclusion was then a The new hemoglobin gene was introduced to E Coli which are excellent for rapidly producing copies of genes and the E Coli exposed to cold temperatures b The result confirmed that the E Coli was better adapted to the cold environment with the new gene sequence These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute c Researchers were able to conclude that the mammoth s hemoglobin gene sequence did specifically code for a mechanism to allow hemoglobin to function despite cold temperatures
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