UMass Amherst KIN 470 - Kin 470 Final Exam Study Guide (35 pages)

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Kin 470 Final Exam Study Guide



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Kin 470 Final Exam Study Guide

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Pages:
35
School:
University of Massachusetts Amherst
Course:
Kin 470 - Exercise Physiology

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Kin 470 Final Exam Study Guide Muscle thermoregulation and physiology of training 1 What are the components of a motor unit a A motor unit is a motor neuron and all the fibers it innervates b Neuromuscular junction i Junction between motor neuron and muscle fiber c Motor end plate i Pocket formed around motor neuron by sarcolemma d Neuromuscular cleft i Short gap between neuron and muscle fiber e Acetylcholine is released from the motor neuron i Causes an end plate potential EPP ii Depolarization of muscle fiber 2 Describe the steps involved in excitation contraction coupling from activation of the alpha motor neuron to actomyosin binding a b Order of events i Release of Ach into NMJ ii Muscle cell action potential propogated iii Ca release from SR lateral sac iv Ca bind to Tn troponin removes blocking action of tropomyosin v Myosin binds to actin cross bridge moves vi Myosin power stroke generates force and or motion of actin filament vii Calcium taken up by SR viii Calcium removal from troponin restores tropomyosin blocking action 3 What are the molecular mechanisms underlying muscle relaxation a Cross bridge moves b Ca2 taken up by SR c Ca2 removal from troponin restores tropomyosin blocking action d relaxation e NOTES i Activation 1 Calcium released 2 Binds to troponin 3 Myosin binds to actin ii Relaxation 1 Calcium back to SR 2 Regulatory proteins prevent myosin and actin from binding 4 What is the role of troponin and tropomyosin in contraction a b troponin i blocks tropomyosin ii calcium binds to troponin allows myosin binding spots on actin to be exposed c tropomyosin i long stringy ii blocks the myosin binding sites on actin iii moves over to expose myosin binding spots on actin when calcium binds to troponin troponin blocking action removed 5 What are the molecular mechanisms that underlie muscle fatigue from intense contractile activity a b failure of Ca release from the sarcoplasmic reticulum c compromised activation of muscle less sensitive to Ca i no



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