BSC 160 1nd Edition Lecture 2Outline of Last Lecture 1. Main Characteristics of Microbes2. History & Relevance of MicrobiologyOutline of Current Lecture 1. Microorganism relationships2. Robert Koch3. History- Vaccines & antimicrobial compoundsCurrent Lecture- Parasitic relationship- 1 benefits, 1 gets hurt- Commensalism- 1 benefits, 1 has no impactCows + gut microbes: Cow eats grass, bacteria has enzymes to break down cellulose to sugar, helps digest- Mutualism- Both benefitBiotechnology & Molecular Biology: Study of infectious disease- Molecular basis of heredity- Laboratory enzymes- Antibiotics- Genetic engineering- Immunity insightRobert Koch- Father of medical microbio. Anthrax4 Postulates: Show specific microbes are for specific diseases1. Microbe is only in diseased animals2. Isolate microbe from diseased animal & grown in other culture3. Inject into healthy mouseDisease reproduces4. Isolate microbe again, show be same as microbe in #2These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.Limtations: 1.) Some microbes can’t be isolated. 2.)Can’t be tested on humansLouis Pasteur- Proved spontaneous contamination is incorrect- Found wine sours because of bacteria contaminationLactic acid- Boiling can destroy microbes- Germ theory of disease: Microbes disease- Fermentation: metabolism following glycosis. Yeast converts sugarethanol- Pasteurize: Heat until bacteria is destroyedHistory- Vaccines & antimicrobial compounds- Small pox- highly contagious. Eradicated 1977. Mortality rate: 25% adults, 40% children- Variolation- Inoculate immune system. Give mild small pox, recover, immuneEdward Jenner: Found people that work with cows that get cowpox, are immune to small pox. Tested on a child- Attenuation- Taking pathogen, weakening by chemical/heat treatment or pass through susceptible host
View Full Document
Unlocking...