Essentials of Genetics 8e Klug Chapter 10 DNA Replication and Recombination 1 Which of the following terms accurately describes the replication of DNA in vivo A conservative B Dispersive C Semiconservative D Nonlinear E Nonreciprocal 2 DNA polymerase III adds nucleotides A to the 3 end of the RNA primer B to the 5 end of the RNA primer C in the place of the primer RNA after it is removed D to both ends of the RNA primer E to internal sites in the DNA template 3 DNA polymerase I is thought to add nucleotides A to the 5 end of the primer B to the 3 end of the primer C in the place of the primer RNA after it is removed D on single stranded templates without need for an RNA primer E in a 5 to 5 direction 4 Which terms accurately reflect the nature of replication of the chromosome in E Coli A Bidirectional and fixed point of initiation B Unidirectional and reciprocal C Unidirectional and fixed point of initiation D Multirepliconic and telomeric E Bidirectional and multirepliconic 5 Which cluster of terms accurately reflects the nature of DNA replication in prokaryotes A Fixed point of initiation bidirectional conservative B Fixed point of initiation unidirectional conservative C Random point of initiation bidirectional semiconservative D fixed point of initiation bidirectional semiconservative E Random point of initiation unidirectional semiconservative 6 The discontinuous aspect of replication of DNA in vivo is caused by A Polymerase slippage B Trinucleotide repeats C The 5 to 3 polarity restriction D Topoisomerases cutting the DNA in a random fashion E sister chromatid exchanges Copyright 2014 Pearson Education Inc 1 7 Structures located at the ends of eukaryotic chromosomes are called A Centromeres B Telomerase C Recessive mutations D Telomeres E Permissive mutations Difference between RNA DNA Looking for T or U Looking at where the hydroxyl group is added 37 In general DNA replicates semiconservatively and bidirectionally TRUE 40 DNA replication occurs in the 5 to 3 direction that is new nucleoside triphosphates are added to the 3 end TRUE 41 DNA strand replication begins with an RNA primer TRUE 42 During replication primase adds a DNA primer to RNA FALSE 44 In ligase deficient strains of E coli DNA and chromosomal replication are unaltered because ligase is not involved in DNA replication FALSE DNA polymerase gyrase helicase ligase 46 A nucleosome is a structure associated with the nuclear membrane It helps maintain a stable relationship between the extracellular matrix and the membrane itself FALSE 47 A characteristic of aging cells is that their telomeres become shorter TRUE 48 Telomerase is an RNA containing enzyme that adds telomeric DNA sequences onto the ends of linear chromosomes TRUE 49 Bacteria are dependent on telomerase to complete synthesis of their chromosome ends FALSE Copyright 2014 Pearson Education Inc 2