Nucleic Acids DNA Tuesday July 1 Reading quiz What group is NOT part of a nucleotide 1 An amine group NH4 2 A phosphate group PO4 3 A 5 carbon sugar 4 A nitrogen containing base What group is NOT part of a nucleotide 1 An amine group NH4 2 A phosphate group PO4 3 A 5 carbon sugar 4 A nitrogen containing base An amine group NH4 A phosphate group A 5 carbon sugarA nitrogen containin 33 8 42 17 What is the monomer of proteins 1 Monosaccharide 2 Fatty Acid 3 Nucleotide 4 Amino Acid What is the monomer of proteins 1 Monosaccharide 2 Fatty Acid 3 Nucleotide 4 Amino Acid MonosaccharideFatty AcidNucleotideAmino Acid8 75 17 0 What type of molecule is this 1 Carbohydrate 2 Lipid 3 Protein 4 Nucleic acid What type of molecule is this 1 Carbohydrate 2 Lipid 3 Protein 4 Nucleic acid CarbohydrateLipidProteinNucleic acid0 50 33 17 What type of molecule is composed of a central carbon attached to a hydrogen atom an NH2 group a COOH group and an R group 1 Monosaccharide 2 Fatty Acid 3 Amino Acid 4 Nucleotide What type of molecule is composed of a central carbon attached to a hydrogen atom an NH2 group a COOH group and an R group 1 Monosaccharide 2 Fatty Acid 3 Amino Acid 4 Nucleotide MonosaccharideFatty AcidAmino AcidNucleotide8 0 92 0 Into what class of organic molecules does this belong 1 Carbohydrate 2 Lipid 3 Protein 4 Nucleic acid Into what class of organic molecules does this belong 1 Carbohydrate 2 Lipid 3 Protein 4 Nucleic acid CarbohydrateLipidProteinNucleic acid25 17 50 8 We share a significant proportion of our DNA sequence with other organisms including yeast A True B False We share a significant proportion of our DNA sequence with other organisms including yeast A True B False TrueFalse17 83 DNA structure and replication PowerPoint Lecture Presentations for Biology Eighth Edition Neil Campbell and Jane Reece Lectures by Chris Romero updated by Erin Barley with contributions from Joan Sharp Copyright 2008 Pearson Education Inc publishing as Pearson Benjamin Cummings Additional Evidence That DNA Is the Genetic Material Sugar phosphate Nitrogenous backbone bases 5 end DNA is a polymer of nucleotides Thymine T Adenine A Cytosine C Phosphate DNA nucleotide Sugar deoxyribose 3 end Guanine G Copyright 2008 Pearson Education Inc publishing as Pearson Benjamin Cummings What is the structure of DNA Sugar phosphate Nitrogenous backbone bases 5 end DNA is a polymer of nucleotides Chargaff s rules 1950 state that in any species A T and G C Copyright 2008 Pearson Education Inc publishing as Pearson Benjamin Cummings Thymine T Adenine A Cytosine C Phosphate DNA nucleotide Sugar deoxyribose 3 end Guanine G Building a Structural Model of DNA Scientific Inquiry What is DNA s structure Maurice Wilkins and Rosalind Franklin used X ray crystallography Copyright 2008 Pearson Education Inc publishing as Pearson Benjamin Cummings Fig 16 6 a Rosalind Franklin b Franklin s X ray diffraction photograph of DNA Results of Franklin and Wilkins and Watson and Crick DNA is helical two strands forming a double helix Copyright 2008 Pearson Education Inc publishing as Pearson Benjamin Cummings Fig 16 1 Watson and Crick built models of a double helix to conform to the X rays and chemistry of DNA Franklin concluded two antiparallel sugar phosphate backbones nitrogenous bases paired in the molecule s interior Copyright 2008 Pearson Education Inc publishing as Pearson Benjamin Cummings Fig 16 7 5 end Hydrogen bond 3 end 1 nm 3 4 nm 3 end 0 34 nm 5 end a Key features of DNA structure b Partial chemical structure c Space filling model Fig 16 7a 1 nm 3 4 nm 5 end Hydrogen bond 3 end 3 end 0 34 nm 5 end a Key features of DNA structure b Partial chemical structure Fig 16 7b c Space filling model POGIL activity on DNA Structure and Replication Choose Lego pieces to form groups four groups of three Work through Question 10 in 15 minutes Check answers to Question 2 with Destiney or Dr Hoffman Be ready to answer Question 9 with clickers Fill in the complementary bases on the strand according to the base pair rule A T C C A G A A T C C A G B G A C C T A C T A G G T C D C T G G A T Fill in the complementary bases on the strand according to the base pair rule A T C C A G A A T C C A G B G A C C T A C T A G G T C D C T G G A T A T C C A GG A C C T AT A G G T CC T G G A T0 0 100 0 Work through Question 16 Note molecules that end in ase are enzymes and the rest of the name tells you something about its function peptidase breaks down proteins or polypeptides Add a question after 16 In one or two complete sentences describe how DNA is replicated DNA replication Animation 1 Animation 2 Animation 3 DNA Structure and Replication http www wehi edu au education wehitv molecular visualisations of dna http www stolaf edu people gianni ni flashanimat molgenetics dna rna2 swf http www dnaftb org http vcell ndsu nodak edu animati ons