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OSU CHEM 2520 - Hell-Vollhard-Zelinsky reaction
School name The Ohio State University
Course Chem 2520- Organic Chemistry II
Pages 4

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2 Hell Vollhard Zelinsky reaction HVZ 19 12 A Bromonation alpha to the acid B Proceeds through an acyl halide enol precursor C Used for synthetic amino acid VIII Biological Applications 19 13 1 Fatty Acids long chain COOHs cis vs trans A Made by acetic acid coupling 2 Long chain carboxylates soaps A Form micelles 3 Natural products Chapter 20 I Reactivity and Structure of COOHs Derivatives 20 1 1 Follow typical addition elimination mechanisms Nucleophilic acyl substitutions NAS 2 Better LGs make easier reactions

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