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Name - Printed___________________________ Signature___________________________ Version 1 Exam 3 – April 1, 2013 BSC 2010, Introductory Biology Part I – Knowing the Vocabulary For questions 1-14 identify which word (if any) fits the given definition, as defined by the textbook and vocabulary lists. 1. “A short stretch of RNA with a free 3′ end, bound by complementary base pairing to the template strand and elongated with DNA nucleotides during DNA replication.“ a. okazaki fragment b. primer c. DNA ligase d. siRNA e. none of the above 2. “The tandemly repetitive DNA at the end of a eukaryotic chromosome's DNA molecule.” a. telomere b. promoter c. bacteriophage d. nuclease e. none of the above 3. “Eukaryotic chromatin that remains highly compacted during interphase and is generally not transcribed.” a. chromosome b. euchromatin c. apochromatin d. heterochromatin e. none of the above 4. “The synthesis of a polypeptide using the genetic information encoded in an mRNA molecule.” a. nucleogenesis b. transcription c. translation d. replication e. none of the above 5. “A specific nucleotide sequence in the DNA of a gene that binds RNA polymerase, positioning it to start transcribing RNA at the appropriate place.” a. inducer b. enhancer c. promoter d. activator e. none of the above6. “A chemical or physical agent that interacts with DNA and can cause a mutation.” a. initiator b. inhibitor c. oncogene d. exon e. none of the above 7. “A specific small molecule that binds to a bacterial repressor protein and changes the repressor's shape so that it cannot bind to an operator, thus switching an operon on.” a. repressor b. activator c. deactivator d. enhancer e. none of the above 8. “The process by which a cell or group of cells become specialized in structure and function.” a. evolution b. transformation c. metamorphosis d. morphometrics e. none of the above 9. “A gene found in viral or cellular genomes that is involved in triggering molecular events that can lead to cancer.” a. oncogene b. operon c. intron d. mutagen e. none of the above 10. “A general outbreak of a disease.” a. differentiation b. pandemic c. endemic d. epidemic e. none of the above 11. “An infectious agent that is a misfolded version of a normal cellular protein.” a. prion b. viroid c. virus d. phage e. none of the above12. “A technique that enables specific nucleotide sequences to be detected in samples of DNA.” a. western blotting b. northern blotting c. polymerase chain reaction (PCR) d. genetic recombination e. none of the above 13. “A small, circular, double-stranded DNA molecule that carries accessory genes separate from those of a bacterial chromosome; in DNA cloning, used as vectors carrying up to about 10,000 base pairs (10 kb) of DNA.” a. plasmid b. primer c. regulatory gene d. cDNA e. none of the above 14. “Describing a cell that can give rise to many, but not all, parts of an organism.” a. totipotent b. pluripotent c. omnipotent d. egg e. none of the above Part II – Understanding the Homework 15. If a sample of double stranded DNA is found to have 20% of its bases composed of adenine, which of the following is an accurate conclusion: a. guanine will make up 70% of the DNA b. guanine will make up 40% of the DNA c. guanine will make up 30% of the DNA d. guanine will make up 20% of the DNA e. None of the above is accurate 16. In DNA replication, how do the leading and lagging strand differ? a. The leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction. b. The leading strand is synthesized at twice the rate of the lagging strand. c. The leading strand is synthesized in short fragments that are ultimately stitched together, whereas the lagging strand is synthesized continuously. d. The leading strand is synthesized by adding nucleotides to the 3' end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5' end. e. The leading strand is synthesized first, and the lagging strand second.17. Which of the following is true of heterochromatin but not of euchromatin? a. It is accessible to enzymes needed for gene expression. b. It becomes less tightly compacted after cell division. c. It includes DNA primarily found in expressed genes. d. It remains tightly coiled or condensed during interphase. e. It contains the genes that determine an organisms sex. 18. The flow of genetic information in a cell proceeds in what sequence? a. from RNA to protein to DNA b. from RNA to DNA to protein c. from protein to RNA to DNA d. from DNA to protein to RNA e. from DNA to RNA to protein 19. Using the genetic code above, which of the following protein sequences would be coded for by the RNA sequence AGA-GGU-GAC? a. Gly-Ser-Glu b. Gly-Ser-Asp c. Arg-Gly-Asp d. Arg-Ser-Glu e. No protein sequence would be produced as the first codon is a stop codon.20. Which of the following types of mutation, resulting in an error in the mRNA just after the AUG start of translation, is likely to have the most serious effect on the polypeptide product? a. a deletion of two nucleotides b. a substitution of the first nucleotide of a GGG codon c. an insertion of a codon d. a deletion of a codon e. a substitution of the third nucleotide in an ACC codon 21. Which of the following is not an event that happens in translation? a. the polypeptide chane elongates by formation of a peptide bond. b. an aminoacyl tRNA molecule binds to the mRNA by means of an anticodon. c. the mRNA is translocated along the ribosome. d. a ribonucluetide is added to the 3' end of the mRNA. e. translation stops when the stop codon is reached. 22. Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If she moves the repressor gene (lac I), along with its promoter, to a position at some several thousand base pairs away from its normal position, which will you expect to occur? a. The lac operon will be expressed continuously. b. The repressor will no longer bind to the inducer. c. The lac operon will function normally. d. The repressor will no longer be made. e. The repressor will no longer bind to the operator. 23. Which of the following


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FSU BSC 2010 - Exam 3

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