-OR _! ---:!: 1 systematic review of randomized controlled tnals rated as a 1+ directly applrcable to target population and overall consistent results 1 OR -Multiple studies rated as 1 + directly applicable to target population and overall consistent results B Multlple studies rated as 2++ directly applicable to target population and: -Overall consistent results OR -Extrapolated evidence from studies rated as 1++ or 1+ C Multiple studies rated as 2+ directly applicable to target population and: -Overall consistent results OR -Extrapolated evidence from studies rated as 2++ Q Evidence level consisting of studies rate as 3 or 4 OR Extrapolated evidence from studies rated as 2++
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