SYLLABUS Course title and number Gene/BIMS 320-502 Term ( FALL 2018 Meeting times and location Rm: VIDI101 C. Time: 9:10-10 AM (M, W And F) Course Description and Prerequisites BASIC genetic principles as applied to biomedical science; Mendelian inheritance, mutagenesis and pedigree analysis; molecular basis of gene function and inherited disease; epi-genetics, stem cells, cancer, neuro-genetics, gene therapy and genetic counseling. All the lectures are designed to understand the basic connection from lesson learned from basic science and how it translates into understanding and modulating human health. From bench to bedside and towards individualized medicine based on genetic and genomic understanding. Credit cannot be given for both GENE 301 and GENE 320. Prerequisites: Junior or senior classification; BIMS major with a minimum overall 2.5 TAMU GPA. Cross-listed with GENE 320 Learning Outcomes or Course Objectives Have a fundamental understanding of basic aspects of human genetics with a focus on translational science that has impacted human health in the post-genomic era. Instructor Information Name Vijay S. Venkatraj Telephone number 979 458 3501 (email is much better, since I am in the lab most times) Email address [email protected] Office hours Anytime (Fix a time via email) Office location Rm : VIDI 333 Textbook and/or Resource Material NO TEXT BOOK ! Printed class notes- Teaching and exam material from power point slides. Grading Policies Refer to the Student Rules regarding Academics at http://student-rules.tamu.edu. Discussed also in first day of class. Course Topics, Calendar of Activities, Major Assignment Dates  BASIC GENETICS:  Introduction  Mitosis and Meiosis Cytogenetics and Molecular Cytogenetics  Cell Cycle and its relation to Physiology and Pathology  DNA Replication  DNA Mutation and Repair  Transcription (coding and non-coding) and Translation and P T modifications  Epigenetics and Epigenomics in Health and Disease.  APPLIED GENETICS:  Cancer as a Genetic Disease  Neuro-Genetics- Basics  Pedigrees, Inheritence Patterns and Disease Genotypes and Phenotypes in Humans  Genome project , CRISPR and Stem Cells  Diagnosis in Post Genomic Era including Ethical Legal Social Issues  Test # Date Time Maximum Grade  Test I: 9/17/18 Class Time 100  Test II: 10/22/18 Class Time 100  Test III: 12/10/18 8 AM to 10AM 100  Take home project: I will explain… 100  Total 400/4=100  Take home project Announcement : 10/1/18  Submit on :- : 11/9/18  EXAM PORTIONS ARE NOT CUMULATIVE! Test FORMAT:  True false: 25 X 2 points = 50 points  Filling in Blanks: 10 X 1 points = 10 points Matching 10 x 1 points = 10 points  Short Essays 5 X 6 points = 30 points  Total = 100 points I Americans with Disabilities Act (ADA) The Americans with Disabilities Act (ADA) is a federal anti-discrimination statute that provides comprehensive civil rights protection for persons with disabilities. Among other things, this legislation requires that all students with disabilities be guaranteed a learning environment that provides for reasonable accommodation of their disabilities. If you believe you have a disability requiring an accommodation, please contact Disability Services, in Cain Hall, Room B118, or call 845-1637. For additional information visit http://disability.tamu.edu Academic Integrity For additional information please visit: http://www.tamu.edu/aggiehonor “An Aggie does not lie, cheat, or steal, or tolerate those who do.”. Attendance Policy: “The University views class attendance as the responsibility of an individual student. Attendance is essential to complete the course successfully. University rules related to excused and unexcused absences are located on-line at http://student-rules.tamu.edu/rule07." Example Grading Scales: Standard Letter Grading Scale: A = 90-100 B = 80-89 C = 70-79 D = 60-69 F = <60 Points Grading Scale: Out of 400 assignable points A = 360-400 points B = 320-359 points C = 280-319 points D = 240-279 points F = <240