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IUPUI BIOL K384 - CK384 Syllabus Fall 2018

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Biochemistry BIOL-K384/CHEM-C384 M/W 12:00 – 1:15 pm LE 100 Course Description: Introductory biochemistry covering the fundamentals of the chemistry of life including biomolecular structure and function, the dependence of biological processes on chemical and physical principles, and the synthesis of and use of energy from carbohydrates and fatty acids. This course is taught jointly between the Departments of Biology and Chemistry & Chemical Biology. Recommended for preprofessional students. Prerequisite for advanced-level Biochemistry and Medicinal Chemistry courses in Chemistry & Chemical Biology and certain advanced courses in Biology. 3 credits Pre/Corequisite: CHEM-C342; Strongly Recommended Prerequisite: BIOL-K101 Instructors: Dr. Brenda Blacklock Dr. Lata Balakrishnan LD 326Z SL 208A (317) 278-8181 (317) 274-1290 [email protected] [email protected] Textbook: Lehninger’s Principles of Biochemistry, 7th Edition, by Nelson and Cox, W.H. Freeman and Company. We will not be formally using Launchpad for this course. There is a study guide/solutions manual available from the publisher; ISBN-13: 978-1-4292-9476-8. Solutions to textbook problems are also available on Calculators: A scientific calculator is essential for this course. Cell phone or programmable/ engineering calculators are never allowed. Canvas: Most course materials will be placed on the combined C/K384 site on CANVAS (FA18-IN-BIOL-K384-25570). Preliminary versions of the lecture slides will be provided in packets at least 1 day before the covered section begins. These slides will serve as a template onto which you should take notes during lecture. Modifications of the posted slides may be made up to the beginning of any class period. Updated lecture slides will be posted as soon as possible. KALTURA: Lectures will be recorded and made available through Kaltura on Canvas. Instructors’ Office Hours and Email Policy: Both instructors will hold office hours outside of lecture and ask that you email to let us know when to expect you. Office hours are the best time to ask questions. Please address your questions to the instructor who covered the material in lecture. Dr. Blacklock: Tues. 9:30 to 10:30 am and Wed. 2:00 to 3:30 pm Dr. Balakrishnan: Thurs. 9:30 to 10:30 am; Friday 9:30 to 10:30 am. You must email ahead of time to arrange to meet; my office is in a hallway behind locked doors (ring doorbell on Door 1 to gain access).. Please use email directly to our email addresses putting the course number in the subject line to contact us with questions outside of office hours. Emails sent during the week (Monday to Friday) will be responded to within 24 hours and those received after 5 pm on Friday may not receive a reply until Monday morning. Biology Resource Center: Free tutoring with C/K384 tutor, Joe Mullis, is available in the Biology Resource Center at the Bepko Learning Center in Taylor Hall, UC 2025A, by appointment only. More information can be found at: Scheme: 3 midterm exams at 100 points each 300 1 cumulative final 200 Online homework questions 75 Total 575 The following grade cutoffs (%) are given for your information: A- 80% C 60% B- 70% D 50% The cutoffs will not be raised from these percentages. Student Learning Outcomes: Students will be able to: 1. Explain the dependence of biological/biochemical processes on the fundamental laws of chemistry and physics. (PUL 2, 3) 2. Apply principles from other disciplines of chemistry to biomolecules. (PUL 2, 3) 3. Describe the structure of proteins, nucleic acids, lipids and carbohydrates including their three-dimensional conformations, organization, and stabilizing interactions. (PUL 2, 3) 4. Apply appropriate mathematical equations to characterize chemical and biochemical phenomena. (PUL 2) 5. Describe the relationships between structure and function of biomolecules. (PUL 2, 3) 6. Describe the inter-relatedness of biomolecular structure, metabolism, and biological systems including details of cellular energy production and storage, catabolism, and regulation. (PUL 2, 3) Examinations: Midterm exams will have a mixture of multiple choice (~60%) and short answer questions (~40%). The cumulative final will be comprised of the American Chemical Society standardized exam (40 multiple choice questions) plus multiple choice/short answer questions covering the final four days of lecture. The course instructors will not answer exam-related questions after 10:00 am on exam days. Backpacks, notes, papers, notebooks, etc. must be stored at the front or side of the room during an exam. Programmable calculators (calculators that save data/information when turned off), laptop computers, cell phones, or PDAs may not be used during exams and must be stored in your backpack. Make-up midterm exams will not be given. If you will miss an exam, a valid documented excuse (e.g. doctor’s note or notification of a scheduled university function) must be provided to both instructors before the beginning of the exam. In emergency situations, such as a sudden illness or accident, you must provide documentation (e.g. doctor’s note or police report) as soon as possible. When valid documentation has been provided, the value of a missed midterm exam will be distributed among the remaining exams (e.g. if midterm exam 1 is missed, midterms 2 and 3 will be worth 133 pts each and the final will be worth 233 pts; if midterm exam 2 is missed, midterm exam 3 will worth 150 pts and the final will be worth 250 pts, if midterm exam 3 is missed, the final will be worth 300 pts). Only one midterm exam may be excused. In the absence of appropriate notification and documentation, a score of zero will be assigned for the missed exam. If you must miss the final exam, you are responsible for contacting the course instructors with a valid documented excuse as soon as possible. A grade of Incomplete may be assigned for the course provided the criteria in IUPUI’s Incomplete grade policy ( are met if a make-up exam can not be scheduled before submission of course grades. Homework: Attaining a working understanding of biochemistry requires the integration of material from many other courses such as

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