Progress Report Week 2: Week of September 11th to September 17th 2008 Liver Phantom for MRI Guided Trans-arterial Chemoembolization Simulation Client: Dr. Wally Block Ph.D. University of Wisconsin – Biomedical Engineering Department Advisor: Dr. William Murphy Ph.D. University of Wisconsin – Biomedical Engineering Department Team: Benjamin Engel, Leader Ryan Carroll, BWIG Eric Printz, Communicator Justin Schmidt, BSAC Problem Statement Liver cancer treatment can often involve higher, more targeted doses of chemotherapy if delivered directly to the liver. Professor Block’s MRI lab is integrating capabilities to guide cancer treatment to the liver using magnetic resonance imaging. Current x-ray treatments significantly over treat the liver because while x-ray can be useful in the visualization of catheters, they can't visualize soft tissue, specifically the tumor. It is proposed to develop a liver phantom that will simulate the arterial vessels of the abdomen as well as the liver in an effort to simulate treatments and train interventional radiologists on the use of the new MRI guided techniques. The project will include adding flow capabilities through the use of a programmable fluid pump to simulate pulsatile flow. Week 2 Goals • Review Professor Block’s research grant to gain a better understanding of project motivation as well as current techniques and research goals • Begin conducting background research on topic • Team meeting to discuss team goals and direction • Setup second meeting with Professor Block to clarify requirements (Scheduled for Tomorrow 3:00 PM at the Wisconsin Institute for Medical Research • Begin tracking down sources/physical models of abdominal and liver vasculature Week 2 Activities Team Member Accomplishments Hours Running Total (Hours) Benjamin Engel Team meeting, individual grant review and development of detailed questions for Professor Block 2.5 2.5 Ryan Carroll Team meeting, second client meeting, contacted individuals within school of medicine to obtain vasculature models 2.5 2.5 Justin Schmidt Team meeting, second client meeting, individual vasculature research, prototype brainstorming 2.5 2.5 Eric Printz Team meeting, second client meeting, individual 2.5 2.5vasculature research/study of current phantom being used by lab Week 2 Accomplishments • Held team meeting to discuss project goals and direction • Individual grant review • Research in areas of project motivation and abdominal and liver vasculature • Set up follow up meeting with Professor Block to further establish requirements and details • Established schedule/agenda for the semester • Contacted people in both school of Medicine and Anatomy Department in an effort to obtain a liver model containing vasculature Week 3 Goals • Clarify project details with client (Professor Block) and have them in writing in the for of a PDS (Product Design Specification) • Launch website/obtain team photo for website • Follow up on initial request for liver models/extensive vasculature research • Obtain information on programmable flow pump and review product user manual in an effort to understand how to program the device Schedule Scheduled Completed Monday of Required Presentation 9/1 9/8 9/15 9/22 9/29 10/6 10/13 10/20 10/27 11/3 11/10 11/17 11/24 12/1 12/8 12/15 Propose project Conduct background research Discuss parameters w/ client Develop PDS Brainstorm/solidify design ideas for initial prototype Midsemester presentation Order materials Construct prototype Safety Testing/improvements Usability Testing w/ interventional radiologists Final Presentation Preparation Final PaperProject Difficulties • No difficulties to report thus far Expenses • No expenses to report thus
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