UCF PCB 3233 - Immunology Exam 2 Chapters 3, 4 Study Guide (2) (2 pages)

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Immunology Exam 2 Chapters 3, 4 Study Guide (2)



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Immunology Exam 2 Chapters 3, 4 Study Guide (2)

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School:
University of Central Florida
Course:
Pcb 3233 - Immunology

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PCB 3233 Exam 2 Study Guide Chpt 3 and 4 Chapter 3 1 When the following receptors are engaged what mechanism is initiated in a phagocyte Mannose receptor CR3 and CR4 or Scavenger receptor 2 When the following receptors are engaged what mechanism is initiated in a macrophage TLR s 3 What do TLR 3 4 5 and 7 bind to 4 Know the TLR4 signaling mechanism All of the extracellular including LBP and intracellular MyD88 TIR domain and IKK NFkB signaling 5 In the previous question what 5 genes that you learned about are transcribed because of the TLR 4 recognition 6 What is the general term given to these 5 gene products Hint 2 part name including what they result in along with what type of molecule they are 7 Know what neutrophils do and what lineage they come from during hematopoiesis 8 What is another name for neutrophils 9 Know the 4 classes of adhesion molecules and which adhesion molecule they bind to Ex LFA 1 binds to ICAM 1 and vascular addressin CD 34 binds to L selectin 10 Know the 4 steps of extravasation 11 How can you tell the difference between a general cytokine vs a chemokine 12 Neutrophil granules and the names of them 13 Respiratory burst associated with neutrophils 14 What are the 2 acute phase proteins you learned about and what can they do I am excluding serum amyloid A from this Hint We talked about each being able to do two things 15 Know all 3 complement pathways What has to be present for them to start the initiating enzyme and all the following components cut in order 16 Name of the complement convertases and their components 17 Type I interferons vs Type II interferons 18 What cells can produce Type I interferons 19 What is the main innate immune cell activated by Type I interferons 20 Know the 2 effector functions of NK cells Hint one is cytotoxic 21 What type of infection do NK cells typically fight against 22 What type of response is created in a cell that an NK cell has targeted virally infected 23 What cytokine does an NK cell secrete to



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