UConn MCB 2410 - pierce_sm_chapter06 (13 pages)

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pierce_sm_chapter06

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Pages:
13
School:
University Of Connecticut
Course:
Mcb 2410 - Genetics

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Chapter Six Pedigree Analysis and Applications 72 Chapter Six Pedigree Analysis and Applications COMPREHENSION QUESTIONS 1 What three factors complicate the task of studying the inheritance of human characteristics 1 Mating cannot be controlled so it is not possible to set up controlled mating experiments 2 Humans have a long generation time so it takes a long time to track inheritance of traits over more than one generation 3 The number of progeny per mating is limited so phenotypic ratios are uncertain 2 Describe the features that will be exhibited in a pedigree in which a trait is segregating with each of the following modes of inheritance autosomal recessive autosomal dominant X linked recessive X linked dominant and Y linked inheritance Pedigrees with autosomal recessive traits will show both affected males and females arising with equal frequency from unaffected parents The trait often appears to skip generations Unaffected people with an affected parent will be carriers Pedigrees with autosomal dominant traits will show both affected males and females arising with equal frequency from a single affected parent The trait does not usually skip generations X linked recessive traits will affect males predominantly and will be passed from an affected male through his unaffected daughter to his grandson X linked recessive traits are not passed from father to son X linked dominant traits will affect both males and females and will be passed from an affected male to all his daughters but not to his sons An affected woman usually heterozygous for a rare dominant trait will pass on the trait equally to half her daughters and half her sons Y linked traits will show up exclusively in males passed from father to son 3 What are the two types of twins and how do they arise The two types of twins are monozygotic and dizygotic Monozygotic twins arise when a single fertilized egg splits into two embryos in early embryonic cleavage divisions They are genetically identical



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