UNC-Chapel Hill MCRO 251 - MCRO Final (81 pages)

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Please use the tables indicated for each disease as flashcards starting points Printing off the PowerPoint is a quick and easy way of doing this I will ask about any information on these tables with the exception of most incubation periods unless this plays an important role in the spread of disease 1 Overview of disease A Read over introduction for all systems B For any disease from Chapter 16 and 19 brief introduction 1 What is a normal pattern of infection a b c d 2 a 3 a 4 a b Incubation time time before you show any signs or symptoms of disease i People are not aware that they are infected Prodromal period start to not feel good malaise when you feel something coming down on you know something is wrong Acute phase when organism is starting to replicate and take ofer space in body i Where you show signs and symptoms of disease together they make the disease syndrome ii Symptoms are felt felt but not measured iii Signs are seen observed you see it like if person is having rash 1 B 1 d iii 1 Ex vomiting diarrhea When are you infectious Infectious during ALL ANY STAGES How do we know what is causing an infection Have to have infectious organism have right dose and culture it What is an infectious dose Infectious dose ID ID of infectious organism in half od animals tested If under ID more than likely to not get infected 1 c Common cold rhinovirus had ID50 of 1 d LD50 lethal dose of infectious organism in half of animals tested C Where does the pathogen come from Ch 19 What is its reservoir Where organisms can grow Reservoir only place organisms can grow If human reservoir hard to determine disease o Only cause diseases in humans How is transmitted o Horizontal transmission refers to all other types of transfers includes person to person or environment to person direct or indirect Direct transmission contact droplet spread o Contact with things that are contaminated Infant with poop all over him Biting food and giving to baby oral microbiota Handshakes kissing