Purdue AGR 12300 - Stuff (7 pages)

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Stuff

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Pages:
7
School:
Purdue University
Course:
Agr 12300 - Introduction to College of Agriculture Interdisciplinary Agriculture Academic Programs

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Schizophrenia Research 176 2016 520 526 Contents lists available at ScienceDirect Schizophrenia Research journal homepage www elsevier com locate schres Impaired error processing in late phase psychosis Four year stability and relationships with negative symptoms Dan Foti a Greg Perlman b Greg Hajcak c Aprajita Mohanty c Felicia Jackson c Roman Kotov b a b c Department of Psychological Sciences Purdue University West Lafayette IN United States Department of Psychiatry Stony Brook University Stony Brook NY United States Department of Psychology Stony Brook University Stony Brook NY United States a r t i c l e i n f o Article history Received 29 January 2016 Received in revised form 6 May 2016 Accepted 9 May 2016 Available online 24 May 2016 Keywords EEG ERP Error related negativity Error positivity Schizophrenia a b s t r a c t Error processing is impaired in psychosis and numerous event related potential studies have found reductions in the error related negativity ERN and more recently the error positivity Pe The stability of reduced ERN Pe in psychosis however is unknown In a previous cross sectional report reduced ERN was associated with negative symptom severity and reduced Pe with a diagnosis of schizophrenia versus other psychosis Here we test the stability of impaired error processing over a four year follow up and relationships with subdimensions of negative symptoms The ERN and Pe were recorded from individuals with psychotic disorders twice 79 individuals were assessed 15 years after rst hospitalization and 69 were assessed at 19 years 59 26 with schizophrenia 33 with other psychotic disorders had data at both assessments At 19 years the Pe was blunted in schizophrenia The ERN and Pe exhibited temporal stability over the four years r 0 59 and 0 60 respectively Reduced ERN and Pe correlated with the negative symptom subdimensions of inexpressivity and avolition respectively and not with psychotic or disorganized symptoms Moreover 15 year ERN predicted an



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